EIF5

By Targets:	c-Myc (1) Sirtuin (1) Small Interfering RNA (siRNA) (4)
By Research Areas:	Cancer (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

RK-9123016	Sirtuin c-Myc	Cancer
RK-9123016 is a potent inhibitor of SIRT2. RK-9123016 inhibits the enzymatic activity of SIRT2 with an IC₅₀ value of 0.18 µM but not other human sirtuin members including SIRT1 and SIRT3 at 100 µM. RK-9123016 increases the acetylation level of eukaryotic translation initiation factor 5A (eIF5A), a physiological substrate of SIRT2, and reduces cell viability of human breast cancer cells accompanied with a decrease in c-Myc expression .

EIF5 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
EIF5 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

EIF5 Human Pre-designed siRNA Set A EIF5 Human Pre-designed siRNA Set A

EIF5A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
EIF5A Human Pre-designed siRNA Set A contains three designed siRNAs for EIF5A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

EIF5A Human Pre-designed siRNA Set A EIF5A Human Pre-designed siRNA Set A

EIF5B Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
EIF5B Human Pre-designed siRNA Set A contains three designed siRNAs for EIF5B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

EIF5B Human Pre-designed siRNA Set A EIF5B Human Pre-designed siRNA Set A

EIF5A2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
EIF5A2 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF5A2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

EIF5A2 Human Pre-designed siRNA Set A EIF5A2 Human Pre-designed siRNA Set A

Cat. No.	Compare	Product Name	Species	Source

	EIF5 Protein, Human (His) Eukaryotic translation initiation factor 5; EIF-5	Human	E. coli
	The EIF5 protein is a key member of the 43S pre-initiation complex (43S PIC) and actively participates in mRNA cap-proximal binding, scanning 5'-untranslated regions and locating start codons. EIF5 Protein, Human (GST) is the recombinant human-derived EIF5 protein, expressed by E. coli , with N-GST labeled tag. The total length of EIF5 Protein, Human (GST) is 150 a.a., with molecular weight of 38-43 kDa.

	EIF5A Protein, Human (His) Eukaryotic translation initiation factor 5A-1; EIF-5A1; Rev-binding factor; EIF-4D	Human	E. coli
	The GSK-3 beta protein is an enzyme that plays a crucial role in multiple cellular processes, including cell proliferation, differentiation, and apoptosis. It regulates various signaling pathways and is involved in the development of several diseases, such as cancer and neurodegenerative disorders. GSK-3 beta is active in its unphosphorylated form and can phosphorylate a wide range of substrates to modulate cellular functions. EIF5A Protein, Human (His) is the recombinant human-derived EIF5A protein, expressed by E. coli , with N-6*His labeled tag. The total length of EIF5A Protein, Human (His) is 154 a.a., with molecular weight of ~19 kDa.

	EIF5 Protein, Human (His-SUMO) 2810011H21Rik; D12Ertd549e; EIF 5; EIF 5A; EIF-5; EIF5; Eukaryotic initiation factor 5; Eukaryotic translation initiation factor 5; IF5_HUMAN; MGC36374; MGC36509	Human	E. coli
	The EIF5 protein is a key member of the 43S pre-initiation complex (43S PIC) and actively participates in mRNA cap-proximal binding, scanning 5'-untranslated regions and locating start codons. EIF5 Protein, Human (His-SUMO) is the recombinant human-derived EIF5 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag. The total length of EIF5 Protein, Human (His-SUMO) is 431 a.a., with molecular weight of 65.2 kDa.

	EIF5A2 Protein, Human (His) Eukaryotic translation initiation factor 5A-2; Eukaryotic initiation factor 5A isoform 2; EIF5A2	Human	E. coli
	EIF5A2 is a translation factor critical for promoting elongation and termination, helping stalled ribosomes encounter specific amino acid environments. EIF5A2 is located between the ribosome exit (E) and peptidyl (P) sites and rescues stalled ribosomes, especially those translating polyproline-containing peptides. EIF5A2 Protein, Human (His) is the recombinant human-derived EIF5A2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of EIF5A2 Protein, Human (His) is 153 a.a., with molecular weight of ~22.0 kDa.


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Cat. No.	Product Name	Application	Reactivity

eIF5A Antibody EIF-5A; EIF5A1; EIF5AI; Eukaryotic initiation factor 5A	WB, IHC-P, IP	Human, Mouse, Rat
eIF5A Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 17 kDa, targeting to eIF5A. It can be used for WB,IHC-P,IP assays with tag free, in the background of Human, Mouse, Rat.

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