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EVT‑401

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-145466
    EVT-401

    		P2X Receptor Apoptosis Inflammation/Immunology
    EVT-401 is an orally active, potent and highly selective P2X7R inhibitor, with an IC50 of 10 nM and a Ki of 7.6 nM for human P2X7R, and an IC50 of 220 nM for mouse P2X7R. EVT-401 promots apoptosis and inducs cell cycle arrest in RA SF, reducs the production of proinflammatory and joint-destructive mediators, and mitigats aggressive phenotypes. EVT-401 exhibits favorable oral bioavailability and a good safety profile, making it suitable for research into rheumatoid arthritis .
    EVT-401
  • HY-178230
    EVT‑401

    		P2X Receptor Inflammation/Immunology
    EVT‑401 is an anti-inflammatory agent. EVT‑401 can be metabolized and exert pharmacological effects in vivo. EVT‑401 can be used for research on inflammatory conditions .
    EVT‑401

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