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EZH2-IN-19

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-163741
    EZH2-IN-19

    		Histone Methyltransferase Cancer
    EZH2-IN-19 (conpound N40) is a potent inhibitor of enhancer of zeste homolog 2 (EZH2) WT, with the IC50 of 0.32 nM. EZH2-IN-19 plays an important role in cancer research .
    EZH2-IN-19
  • HY-181320
    PROTAC EZH2 Degrader-19

    		PROTACs Histone Methyltransferase Cancer
    PROTAC EZH2 Degrader-19 (compound 6) is a is a PROTAC protein degrader targeting EZH2 with an IC50 of 15.00 nM. PROTAC EZH2 Degrader-19 induces strong degradation of all PRC2 subunits (EZH2, SUZ12, EED, RbAp48) in a concentration- and time-dependent manner.PROTAC EZH2 Degrader-19 exhibits antiproliferative effects in cancer cells.PROTAC EZH2 Degrader-19 can be used for the research of cancer .
    PROTAC EZH2 Degrader-19
  • HY-181321
    Thalidomide-4-O-C9-Br

    		E3 Ligase Ligand-Linker Conjugates Others
    Thalidomide-4-O-C9-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and a linker used in PROTAC technology. Thalidomide-4-O-C9-Br can be connected to the ligand for protein by a linker to form PROTAC EZH2 Degrader-19 (HY-181320) .
    Thalidomide-4-O-C9-Br

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