EZH2-IN-19
EZH2-IN-19 (conpound N40) is a potent inhibitor of enhancer of zeste homolog 2 (EZH2) WT, with the IC50 of 0.32 nM. EZH2-IN-19 plays an important role in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 3026848-13-2
- Formula: C40H55N7O3
- Molecular Weight:681.91
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Histone Methyltransferase Isoforms
More
Biological Activity
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EZH2 WT 0.32 nM (IC50) |
EZH2 Y641F mutant type 0.03 nM (IC50) |
EZH2 Y641N 0.08 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
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| KARPAS-422 | IC50 |
3.52 nM
Compound: N40
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Antiproliferative activity against human KARPAS-422 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 method
Antiproliferative activity against human KARPAS-422 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 method
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[PMID: 38640588] |
Chemical Information
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CAS No. 3026848-13-2
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Molecular Weight 681.91
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Formula C40H55N7O3
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SMILES
CCN(C1CCC(CC1)N(C)C)C2=CC(C3=CC=C4C(N(C(N4C5CCN(C)CC5)=O)C)=C3)=CC(C(NCC6=C(C=C(NC6=O)C)C)=O)=C2C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EZH2-IN-19 Related Classifications
HY-163741 Related Classifications
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