2. Signaling Pathways
  3. Epigenetics
  4. Histone Methyltransferase
  5. PRMT5 Isoform

PRMT5

 

PRMT5 Related Products (9):

Cat. No. Product Name Effect Purity
  • HY-139611
    MRTX-1719
    		Inhibitor 99.28%
    MRTX-1719 is a potent first-in-class selective inhibitor of the PRMT5/MTA complex, with an IC50 of less than 10 nM in PRMT5/MTA MTAPDEL SDMA cells.
  • HY-128579
    DW14800
    		Inhibitor 99.12%
    DW14800 is a protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC50 of 17 nM.
  • HY-139611C
    MRTX-1719 hydrochloride
    		Inhibitor 99.22%
    MRTX-1719 hydrochloride is a potent first-in-class selective inhibitor of the PRMT5/MTA complex, with an IC50 of less than 10 nM in PRMT5/MTA MTAPDEL SDMA cells.
  • HY-149005
    PRMT5-IN-19
    		Inhibitor
    PRMT5-IN-19 (Compound 41) is an selective orally active non-nucleoside PRMT5 inhibitor with IC50 values of 23.9 nM (radioactive biochemical assay) and 47 nM (AlphaLISA assay).
  • HY-139611B
    (S)-MRTX-1719
    		Inhibitor
    (S)-MRTX-1719 (example 16-7) is the S-enantiomer of MRTX-1719.
  • HY-P3821
    PRMT5-IN-22
    		Inhibitor
    PRMT5-IN-22 (compound 53) is an inhibitor of protein arginine methyltransferase 5 (PRMT5) with anti-tumor activity.
  • HY-P3822
    PRMT5-IN-23
    		Inhibitor
    PRMT5-IN-23 (compound 50) is an inhibitor of protein arginine methyltransferase 5 (PRMT5) with anti-tumor activity.
  • HY-134883
    PRMT5-IN-4
    		Inhibitor
    PRMT5-IN-4 (compound AAA-1) is a PRMT5 inhibitor.
  • HY-150081
    PRMT5-IN-21
    		Inhibitor
    PRMT5-IN-21 (compound 1) is a potent cyclonucleoside PRMT5 inhibitor.