1616391-87-7
1616391-87-7
Chemical Structure
GSK591
Synonym(s): EPZ015866; GSK3203591
- CAS No.: 1616391-87-7
- Formula:C22H28N4O2
- Molecular Weight:380.48
IUPAC Name: (S)-2-(cyclobutylamino)-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)isonicotinamide
InChIKey: TWKYXZSXXXKKJU-FQEVSTJZSA-N
SMILES: O=C(C1=CC(NC2CCC2)=NC=C1)NC[C@H](O)CN3CC4=C(C=CC=C4)CC3
Biological Activity: GSK591 (EPZ015866), a chemical probe, is a potent and selective inhibitor of protein methyltransferase 5 (PRMT5) with an IC50 of 4 nM[1].
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GSK591 | 99.91% | GSK591 (EPZ015866), a chemical probe, is a potent and selective inhibitor of protein methyltransferase 5 (PRMT5) with an IC50 of 4 nM. | ||||||||||||||||||||
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GSK591 (Standard) | ≥98% | GSK591 (Standard) is the analytical standard of GSK591 (HY-100235). This product is intended for research and analytical applications. GSK591 (EPZ015866), a chemical probe, is a potent and selective inhibitor of protein methyltransferase 5 (PRMT5) with an IC50 of 4 nM. | ||||||||||||||||||||
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References
Keywords
