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MS4322  (Synonyms: YS43-22)

Cat. No.: HY-141877 Purity: 98.28%
COA Handling Instructions

MS4322 (YS43-22) is a first-in-class PRMT5 degrader and a valuable chemical tool (PROTAC) for exploring the PRMT5 functions in health and disease.

For research use only. We do not sell to patients.

MS4322 Chemical Structure

MS4322 Chemical Structure

CAS No. : 2375432-47-4

Size Price Stock Quantity
5 mg USD 1300 In-stock
Estimated Time of Arrival: December 31
10 mg USD 2100 In-stock
Estimated Time of Arrival: December 31
25 mg USD 4200 In-stock
Estimated Time of Arrival: December 31
50 mg USD 6700 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of MS4322:

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  • References

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Description

MS4322 (YS43-22) is a first-in-class PRMT5 degrader and a valuable chemical tool (PROTAC) for exploring the PRMT5 functions in health and disease.

IC50 & Target

VHL

 

Molecular Weight

1101.32

Formula

C55H76N10O12S

CAS No.
SMILES

O=C(C1=NC=NC(NC2CN(C(COCCOCCOCCOCCOCC(N[[email protected]](C(N3[[email protected]](C(N[[email protected]](C4=CC=C(C5=C(C)N=CS5)C=C4)C)=O)C[[email protected]@H](O)C3)=O)C(C)(C)C)=O)=O)C2)=C1)NC[[email protected]](O)CN6CC7=C(C=CC=C7)CC6

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (90.80 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9080 mL 4.5400 mL 9.0800 mL
5 mM 0.1816 mL 0.9080 mL 1.8160 mL
10 mM 0.0908 mL 0.4540 mL 0.9080 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
MS4322
Cat. No.:
HY-141877
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