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  3. HOOCCH2O-PEG4-CH2COOH

HOOCCH2O-PEG4-CH2COOH 

Cat. No.: HY-124780 Purity: ≥95.0%
Handling Instructions

HOOCCH2O-PEG4-CH2COOH, compound 5, is a symmetric PEG linker, used for the synthesis of the first class of Homo-PROTAC.

For research use only. We do not sell to patients.

HOOCCH2O-PEG4-CH2COOH Chemical Structure

HOOCCH2O-PEG4-CH2COOH Chemical Structure

CAS No. : 77855-75-5

Size Price Stock Quantity
10 mg USD 55 In-stock
Estimated Time of Arrival: December 31
50 mg USD 160 In-stock
Estimated Time of Arrival: December 31
100 mg USD 260 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Description

HOOCCH2O-PEG4-CH2COOH, compound 5, is a symmetric PEG linker, used for the synthesis of the first class of Homo-PROTAC[1].

Molecular Weight

310.30

Formula

C₁₂H₂₂O₉

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (322.27 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2227 mL 16.1134 mL 32.2269 mL
5 mM 0.6445 mL 3.2227 mL 6.4454 mL
10 mM 0.3223 mL 1.6113 mL 3.2227 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (8.06 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (8.06 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (8.06 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
HOOCCH2O-PEG4-CH2COOH
Cat. No.:
HY-124780
Quantity:
MCE Japan Authorized Agent: