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FABP4

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By Targets:	FABP (7) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cardiovascular Disease (3) Inflammation/Immunology (2) Metabolic Disease (5)

8

Inhibitors & Agonists

3

Recombinant Proteins

1

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

FABP4 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FABP4 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FABP4 Human Pre-designed siRNA Set A FABP4 Human Pre-designed siRNA Set A

FABP4-IN-3	FABP	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
FABP4-IN-3 (compound C3) is a highly selective *FABP4* inhibitor (FABP4 K_i = 25 ± 3 ^a nM, FABP3 K_i = 15.03 μM) which exhibits a 601-fold selectivity over FABP3. FABP4-IN-3 also shows metabolic stability and potent cellular anti-inflammatory activity, making it promising to get involved in the research of metabolic disease, cardiac dysfunction and inflammation-related disease .

FABP4-IN-2	FABP	Inflammation/Immunology
FABP4-IN-2 (Compd 10g) is a selective and orally active *FABP4* inhibitor with the K_i values of 0.51 μM for FABP4, 33.01 μM for FABP3. FABP4-IN-2 can be used in the research of inflammation-related diseases .

FABP4/5-IN-4	FABP	Metabolic Disease
FABP4/5-IN-4 (compound E1) is a potent inhibitor of *FABP4 and FABP5, with the IC₅₀s of 3.78 μM and 5.72 μM, respectively. FABP4*/5-IN-4 plays an important role in metabolism disorder like diabetes mellitus .

FABP4/5-IN-5	FABP	Metabolic Disease
FABP4/5-IN-5 (compound D9) is a potent inhibitor of *FABP4 and FABP*5,? with the IC₅₀s of 4.68 μM and 10.72 μM, respectively.FABP4/5-IN-5 plays an important role in metabolism disorder like diabetes mellitus .

HY-148665

FABP-IN-2

FABP Others

FABP-IN-2 is a novel FABP3 ligand. FABP-IN-2 inhibits FABP3/FABP4 with an IC₅₀ of 1.16 μM and 4.27 μM respectively .

BMS-309403 10+ Cited Publications	FABP	Cardiovascular Disease Metabolic Disease
BMS-309403 is a potent, orally active and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor with K_is of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells .

BMS-309403 sodium 10+ Cited Publications	FABP	Cardiovascular Disease Metabolic Disease
BMS-309403 sodium is a potent, orally active, and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor, with K_is of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 sodium interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 sodium improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells .

Species:	Human (1) Mouse (2)
Tag:	His (3)
Source:	HEK293 (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

	FABP4 Protein, Mouse (His) Adipocyte-type fatty acid-binding protein; FABP4; AFABP	Mouse	E. coli
	The FABP4 protein binds hormone receptors, fatty acids, and transports them. It regulates thermogenesis, brown fat cell differentiation, and response to lithium ion. It is located in the cytoplasm and nucleus, and is expressed in adipose tissue, CNS, genitourinary system, gut, and heart. It shares orthology with human FABP4. Biased expression is seen in subcutaneous and genital fat pads. FABP4 Protein, Mouse (His) is the recombinant mouse-derived FABP4 protein, expressed by E. coli , with N-His labeled tag. The total length of FABP4 Protein, Mouse (His) is 131 a.a., with molecular weight of ~15.63 kDa.

	FABP4 Protein, Mouse (HEK293, His) Adipocyte-type fatty acid-binding protein; FABP4; AFABP	Mouse	HEK293
	FABP4 Protein, a member of the calycin superfamily, is classified within the fatty-acid binding protein (FABP) family. FABP4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived FABP4 protein, expressed by HEK293, with C-His labeled tag. The total length of FABP4 Protein, Mouse (HEK293, His) is 132 a.a., with molecular weight of ~15 kDa.

	FABP4 Protein, Human (His) rHuFatty acid-binding protein adipocyte/FABP4, His; Fatty Acid-Binding Protein Adipocyte; Adipocyte Lipid-Binding Protein; ALBP; Adipocyte-Type Fatty Acid-Binding Protein; A-FABP; AFABP; Fatty Acid-Binding Protein 4	Human	E. coli
	FABP4 Protein, expressed mainly in adipocytes, crucially mediates lipid and retinoic acid transport. It binds long-chain fatty acids and retinoic acid, facilitating delivery to nuclear receptors. Functioning as a monomer and forming homodimers, FABP4 interacts with PPARG, contributing to its involvement in fatty acid metabolism and signaling pathways. FABP4 Protein, Human (His) is the recombinant human-derived FABP4 protein, expressed by E. coli , with N-6*His labeled tag. The total length of FABP4 Protein, Human (His) is 131 a.a., with molecular weight of ~15.0 kDa.

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