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GDC+0941

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-50094
    Pictilisib
    65+ Cited Publications

    GDC-0941

    		 PI3K Autophagy Apoptosis Cancer
    Pictilisib (GDC-0941) is a potent inhibitor of PI3Kα/δ with an IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold).
    Pictilisib
  • HY-20180
    Pictilisib dimethanesulfonate
    65+ Cited Publications

    GDC-0941 dimethanesulfonate ; GDC-0941 (2 MeSO3H salt)

    		 PI3K Autophagy Apoptosis Cancer
    Pictilisib dimethanesulfonate (GDC-0941 dimethanesulfonate) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold).
    Pictilisib dimethanesulfonate
  • HY-50094R
    Pictilisib (Standard)

    GDC-0941 (Standard)

    		 PI3K Autophagy Apoptosis Reference Standards Cancer
    Pictilisib (Standard) is the analytical standard of Pictilisib. This product is intended for research and analytical applications. Pictilisib (GDC-0941) is a potent inhibitor of PI3Kα/δ with an IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold).
    Pictilisib (Standard)
  • HY-20180R
    Pictilisib dimethanesulfonate (Standard)

    GDC-0941 dimethanesulfonate (Standard); GDC-0941 (2 MeSO3H salt) (Standard)

    		 PI3K Autophagy Apoptosis Reference Standards Cancer
    Pictilisib (dimethanesulfonate) (Standard) is the analytical standard of Pictilisib (dimethanesulfonate). This product is intended for research and analytical applications. Pictilisib dimethanesulfonate (GDC-0941 dimethanesulfonate) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold).
    Pictilisib dimethanesulfonate (Standard)
  • HY-117744
    NMS-P645

    		Pim Endocrinology Cancer
    NMS-P645 is a PIM1 inhibitor. NMS-P645 exhibits anti-proliferative activity when combined with GDC-0941 (HY-50094) in TMPRSS2/ERG positive and negative PCa cells. NMS-P645 can reverse PIM1-induced pro-survival signals in prostate cells. NMS-P645 can be studied in research on prostate cancer .
    NMS-P645

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