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IL12B

" in MedChemExpress (MCE) Product Catalog:
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  • HY-P7370
    IL-12 Protein, Rat (CHO)

    rRtIL-12; CLMF; IL-12A; IL-12B

    		 Rat CHO
    IL-12 Protein, Rat (CHO) is an inflammatory cytokine that promotes the response of the immune system.
  • HY-P73164
    IL-12 beta Protein, Rat (HEK293, His)

    Interleukin-12 subunit beta; IL-12B; CLMF p40; IL-12 subunit p40; NKSF2; IL12B

    		 Rat HEK293
    IL-12 beta Protein, also known as natural killer cell stimulatory factor 2, is a common subunit (p40) of IL-12 and IL-23. IL-12 is a inflammatory factor expressed by activated macrophages, and involves in Th1-type immune response against cancer. IL-12 beta Protein located outside the cell membrane, involves in singalling mediated by Jak-STAT. IL-12 beta Protein consists of 335 amino acids (M1-S335) with a lg-like domain (43-90 a.a). IL-12 beta Protein, Rat (M1-S335) is produced in HEK293 cells with a C-Terminal His-tag.
  • HY-P72598
    IL-12 Protein, Rat (HEK293, His)
    1 Publications Verification

    Interleukin-12; IL-12

    		 Rat HEK293
    IL-12 Protein forms the IL-12 cytokine and IL-35 cytokine. It regulates T-cell and natural killer-cell responses, stimulates interferon-gamma production, and promotes T-helper 1 cell differentiation. Its receptor, composed of IL12R1 and IL12R2 subunits, activates STAT4 and regulates gene expression. In the context of IL-35, IL-12 Protein maintains immune homeostasis and acts as an immune-suppressive cytokine. It signals through unconventional receptors and requires STAT1 and STAT4 transcription factors. It also interacts with NBR1 to promote IL-12 secretion. IL-12 Protein, Rat (HEK293, His) is a recombinant protein dimer complex containing rat-derived IL-12 protein, expressed by HEK293, with C-6*His labeled tag. IL-12 Protein, Rat (HEK293, His), has molecular weight of 25-35 & 40-50 kDa, respectively.
  • HY-P74835
    IL-12 beta Protein, Rat (HEK293, Fc)

    Interleukin-12 subunit beta; IL-12B; CLMF p40; IL-12 subunit p40; NKSF2; IL12B

    		 Rat HEK293
    IL-12 beta Protein, also known as natural killer cell stimulatory factor 2, is a common subunit (p40) of IL-12 and IL-23. IL-12 is a inflammatory factor expressed by activated macrophages, and involves in Th1-type immune response against cancer. IL-12 beta Protein located outside the cell membrane, involves in singalling mediated by Jak-STAT. IL-12 beta Protein consists of 335 amino acids (M1-S335) with a lg-like domain (43-90 a.a). IL-12 beta Protein, Rat (M1-S335) is produced in HEK293 cells with a C-Terminal hFc-tag.

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