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Results for "

JT-001

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-145119AS

    JT001; VV116; GS-621763-d1 hydrobromide

    SARS-CoV RSV Influenza Virus Infection
    Mindeudesivir (JT001; VV116; GS-621763-d1) hydrobromide is a deuterated version of Remdesivir (HY-104077), a highly orally active nucleoside antiviral against SARS-CoV-2 and respiratory syncytial virus (RSV). Mindeudesivir hydrobromide retains the antiviral activity of Remdesivir against COVID-19, and is the first domestically produced deuterium targeting the COVID-19 .
    Mindeudesivir hydrobromide
  • HY-145119S

    JT001 free base; VV116 free base; GS-621763-d1

    Isotope-Labeled Compounds Others
    GS-621763-d1 is the deuterium labeled GS-621763 (HY-145119) . GS-621763, an orally bioavailable proagent of GS-441524, shows antiviral activity against SARS-CoV-2 pathogenesis in mice .
    Mindeudesivir
  • HY-156034A

    NLRP3-IN-19 sodium

    NOD-like Receptor (NLR) Inflammation/Immunology
    JT001 (NLRP3-IN-19) sodium is a potent, specific and orally active inhibitor of NLRP3. JT001 sodium can inhibit NLRP3 inflammasome assembly, resulting in the inhibition of cytokine release and the prevention of pyroptosis. JT001 sodium can be used for the research of nonalcoholic steatohepatitis and liver fibrosis .
    <em>JT001</em> sodium
  • HY-156034

    NLRP3-IN-19

    NOD-like Receptor (NLR) Inflammation/Immunology
    JT001 (NLRP3-IN-19) is a potent, specific and orally active inhibitor of NLRP3. JT001 can inhibit NLRP3 inflammasome assembly, resulting in the inhibition of cytokine release and the prevention of pyroptosis. JT001 can be used for the research of nonalcoholic steatohepatitis and liver fibrosis .
    NLRP3-IN-19

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