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Results for "

KLK7

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

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Peptides

3

Recombinant Proteins

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Cat. No. Compare Product Name Species Source
  • HY-P70163
    Kallikrein-7 Protein, Human (HEK293, His, solution)

    rHuKallikrein 7/KLK7, His ; Kallikrein-7; hK7; Serine Protease 6; Stratum Corneum Chymotryptic Enzyme; hSCCE; KLK7; PRSS6; SCCE

    		 Human HEK293
    Kallikrein-7 Protein (KLK7), a member of the tissue kallikrein family, is a first protease target of vaspin inhibited by classical serpin mechanism with high specificity in vitro. KLK7 cleaves human insulin in the A- and B-chain. KLK7 a serine protease with chymotrypsin-like activity which was involved in the regulated desquamation of terminally differentiated keratinocytes. KLK7 mediates the disruption of corneodesmosomes, the cell–cell adhesion junctions of corneocyites, by hydrolyzing the two mayor cadherins (corneodesmosin and desmocollin 1) in the extracellular region of these junctions. KLK7 overexpression and/or increased activity result in over-desquamation. Kallikrein-7 Protein, Human (HEK293, His, solution) is the recombinant human-derived Kallikrein-7 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Kallikrein-7 Protein, Human (HEK293, His, solution) is 230 a.a., with molecular weight of ~30.0 kDa.
  • HY-P76466
    Kallikrein-7 Protein, Human (HEK293, His)

    Kallikrein-7; Serine protease 6; hSCCE; KLK7; PRSS6; SCCE

    		 Human HEK293
    Kallikrein-7 is a serine protease with chymotrypsin-like activity that plays a role in intercellular proteolysis, leading to epidermal exfoliation. It is involved in cancer invasion and metastasis, and elevated expression is associated with poor prognosis and cancer progression. Kallikrein-7 Protein, Human (HEK293, His) is the recombinant human-derived Kallikrein-7 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of Kallikrein-7 Protein, Human (HEK293, His) is 231 a.a., with molecular weight of 30-33 KDa.
  • HY-P70883
    Kallikrein-7 Protein, Mouse (HEK293, His)

    Kallikrein-7; KLK7; Serine protease 6; Stratum corneum chymotryptic enzyme; Thymopsin; kallikrein-related peptidase 7; PRSS6; SCCEkallikrein-7

    		 Mouse HEK293
    Kallikrein-7 is an important contributor to skin integrity and may catalyze the degradation of intercellular adhesive structures that are critical for continuous cell shedding. Kallikrein-7 exhibits cleavage activity against insulin A and B chains, with specificity for aromatic residues at position P1 indicating versatility in substrate recognition. Kallikrein-7 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Kallikrein-7 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Kallikrein-7 Protein, Mouse (HEK293, His) is 228 a.a., with molecular weight of 28-35 kDa.

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