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Isoforms Recommended: K-Ras
Results for "

KRAS G13C

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Isotope-Labeled Compounds

1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-179536
    KRAS-IN-49

    		Ras Cancer
    KRAS-IN-49 (compound 7b) is a selective and covalent KRAS G13C inhibitor. KRAS-IN-49 covalently binds to Cys13 of KRAS G13C. KRAS-IN-49 can be used for non-small cell lung cancer (NSCLC) research .
    KRAS-IN-49
  • HY-176353S
    KRAS 2B G13C mutant, Arg-13C6,15N4, Lys-13C6,15N2

    		Isotope-Labeled Compounds Cancer
    KRAS 2B G13C mutant, Arg- 13C36, 15N4, Lys- 13C6, 15N2 is the 13C- and 15N-labeled KRAS 2B G13C mutant.
    KRAS 2B G13C mutant, Arg-13C6,15N4, Lys-13C6,15N2
  • HY-179534
    G13Ci-22

    		Ras Cancer
    G13Ci-22 is a MRTX1133 (HY-134813) based KRAS G13C inhibitor. G13Ci-22 can be used for non-small cell lung cancer (NSCLC) research .
    G13Ci-22
  • HY-186086
    RM-041

    		Ras Cancer
    RM-041 is a selective, orally active KRAS G13C (ON) inhibitor that forms a covalent complex with KRAS G13C (ON) and Cyclophilin A. RM-041 blocks the binding of RAS effector proteins via steric hindrance, and then covalently binds to Cys-13 to form an irreversible inhibitory complex, thereby inhibiting the proliferation of KRAS G13C mutant cancer cells. RM-041 induces regression of KRAS G13C tumors in cellular and xenograft tumor models. RM-041 exerts a synergistic effect when combined with upstream node inhibitors (such as SHP2 inhibitors). RM-041 can be used for the research of non-small cell lung cancer .
    RM-041

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