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Results for "

MNNG

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-128612
    Methylnitronitrosoguanidine
    4 Publications Verification

    MNNG

    		 DNA Alkylator/Crosslinker Cancer
    Methylnitronitrosoguanidine (MNNG) is an orally active alkylating agent with toxic and mutagenic effects. Methylnitronitrosoguanidine can as a carcinogen and mutagen . 50% water content, specifications are based on dry weight.
    Methylnitronitrosoguanidine
  • HY-W275553
    4-Decanol

    		Others Infection
    4-Decanol is an antimutagenic compound, that can be isolated from mustard leaves. 4-Decanol inhibits mutagenic activities of $AFB_1$ and MNNG in Salmonella typhimurium TA100 .
    4-Decanol
  • HY-149308
    MKA031

    		Macrophage migration inhibitory factor (MIF) Infection
    MKA031 (compound 6y) is a non-competitive MIF inhibitor with an IC50 value of 1.7 μM. MKA031 (compound 6y) interferes with MIF/AIF interaction, MIF nuclear translocation, and N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced dependent cell death. MKA031 can be used in the study of chronic hepatitis C virus infection .
    MKA031
  • HY-115996
    Antitumor agent-51

    		Others Cancer
    Antitumor agent-51 possesses potent and selective inhibitory for osteosarcoma cell growth and migration with IC50 of 21.9 nM in MNNG/HOS cells. Antitumor agent-51 has a considerable bioavailability and a low toxicity .
    Antitumor agent-51
  • HY-127039
    Antipain

    		Ser/Thr Protease DNA/RNA Synthesis Metabolic Disease Cancer
    Antipain is a protease inhibitor isolated from Actinomycetes. Antipain inhibits N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations. Antipain restricts uterine DNA synthesis and function in mice .
    Antipain
  • HY-127034
    Antipain dihydrochloride

    		Ser/Thr Protease DNA/RNA Synthesis Metabolic Disease Cancer
    Antipain dihydrochloride is a protease inhibitor isolated from Actinomycetes. Antipain dihydrochloride inhibits N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations. Antipain dihydrochloride restricts uterine DNA synthesis and function in mice .
    Antipain dihydrochloride
  • HY-50683S
    JNJ-38877605-d1

    		c-Met/HGFR Cancer
    JNJ-38877605-d1 (compound DO-2) is a highly selective MNNG HOS transforming (MET) inhibitor. JNJ-38877605-d1 is thought to diminish the formation of the Aldehyde Oxidase 1 inactive metabolite M3 .
    JNJ-38877605-d1

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