JNJ-38877605-d1
JNJ-38877605-d1 (compound DO-2) is a highly selective MNNG HOS transforming (MET) inhibitor. JNJ-38877605-d1 is thought to diminish the formation of the Aldehyde Oxidase 1 inactive metabolite M3.
For research use only. We do not sell to patients.
- CAS No.: 1936472-36-4
- Formula: C19H12DF2N7
- Molecular Weight:378.36
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| EBC-1 | IC50 |
17 nM
Compound: 54
|
Antiproliferative activity against human EBC-1 cells assessed as inhibition of cell growth
Antiproliferative activity against human EBC-1 cells assessed as inhibition of cell growth
|
[PMID: 37262349] |
| MKN-45 | IC50 |
25 nM
Compound: 54
|
Antiproliferative activity against human MKN-45 cells assessed as inhibition of cell growth
Antiproliferative activity against human MKN-45 cells assessed as inhibition of cell growth
|
[PMID: 37262349] |
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1936472-36-4
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Unlabeled Cas 943540-75-8
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Appearance Solid
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Molecular Weight 378.36
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Formula C19H12DF2N7
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Color White to off-white
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SMILES
FC(C1=CC=C(N=C([2H])C=C2)C2=C1)(F)C3=NN=C4N3N=C(C5=CN(C)N=C5)C=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)