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Results for "

PGD1

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

3

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108259

    PGE synthase Inflammation/Immunology
    HQL-79, a potent, selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, highly selectively inhibits the synthesis of PGD2, and acts as an anti-allergic agent, with a Kd of 0.8 μM and an IC50 of 6 μM. Shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS .
    HQL-79
  • HY-113096

    PGD1

    Endogenous Metabolite Metabolic Disease
    Prostaglandin D1 is a prostanoid which causes contractile and relaxant on isolated human pial arteries, it is also an inhibitor of ADP-induced platelet aggregation with an IC50 value of 320 ng/ml. Prostaglandin D1 can be used for metabolic research [1] .
    Prostaglandin D1
  • HY-134860

    Prostaglandin Receptor Metabolic Disease
    Prostaglandin D1 (PGD1) alcohol is the synthetic analog of PGD1 with a primary alcohol in place of the C-1 carboxyl [1].
    Prostaglandin D1 alcohol
  • HY-113096S

    PGD1-d4

    Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    Prostaglandin D1-d4 (PGD1-d4) is deuterium labeled Prostaglandin D1. Prostaglandin D1 is a prostanoid which causes contractile and relaxant on isolated human pial arteries, it is also an inhibitor of ADP-induced platelet aggregation with an IC50 value of 320 ng/ml. Prostaglandin D1 can be used for metabolic research [1] .
    Prostaglandin D1-d4
  • HY-110167

    PGE synthase Ligands for Target Protein for PROTAC Cancer
    TFC-007, a selective hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, show high inhibitory activity against H-PGDS enzyme (IC50 value of 83 nM). TFC-007 can be used for composing H-PGDS degradation inducer PROTAC(H-PGDS)-1 (TFC-007 binds to H-PGDS, and Pomalidomide binds to cereblon) [1].
    TFC 007
  • HY-108259R

    Reference Standards PGE synthase Inflammation/Immunology
    HQL-79 (Standard) is the analytical standard of HQL-79 (HY-108259). This product is intended for research and analytical applications. HQL-79, a potent, selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, highly selectively inhibits the synthesis of PGD2, and acts as an anti-allergic agent, with a Kd of 0.8 μM and an IC50 of 6 μM. Shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS .
    HQL-79 (Standard)
  • HY-W339838S

    14:0 Lyso PG-d27 sodium

    Isotope-Labeled Compounds Cancer
    1-Myristoyl-2-hydroxy-sn-glycero-3-PG-d27 sodium (14:0 Lyso PG-d27) is the deuterium labeled 1-Myristoyl-2-hydroxy-sn-glycero-3-PG sodium (HY-W339838). 1-Myristoyl-2-hydroxy-sn-glycero-3-PG sodium is a lysophospholipid containing myristic acid (14:0) at the sn-1 position. It has been used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
    1-Myristoyl-2-hydroxy-sn-glycero-3-PG-d27 sodium
  • HY-145507S

    1-Palmitoyl-2-hydroxy-sn-glycero-3-PG-d31 ammonium; 16:0 Lyso PG-d31 ammonium; PG(16:0/0:0)-d31 ammonium; 1-Hexadecanoyl-sn-glycero-3-phospho-(1'racglycerol)-d31 ammonium

    Isotope-Labeled Compounds Metabolic Disease
    1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol)-d31 ammonium (1-Palmitoyl-2-hydroxy-sn-glycero-3-PG-d31 ammonium) is the deuterium labeled 1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) ammonium (HY-145507). 1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (16:0 Lyso PE) sodium is a lysophospholipid containing palmitic acid (16:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
    1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol)-d31 ammonium

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