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Results for "

Pomalidomide 4'-alkylC3-azide

" in MedChemExpress (MCE) Product Catalog:

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-139341
    Pomalidomide 4'-alkylC3-azide

    		E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide 4'-alkylC3-azide (compound 2a) is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide 4'-alkylC3-azide can be used in the synthesis of PROTAC .
    Pomalidomide 4'-alkylC3-azide
  • HY-174401
    PROTAC HDAC6 degrader 5

    		PROTACs HDAC Ligands for E3 Ligase Cancer
    PROTAC HDAC6 degrader 5 (Compound 5a) is a highly selective PROTAC targeting HDAC6. PROTAC HDAC6 degrader 5 can effectively degrade HDAC6 in cells (IC50 = 43 nM). PROTAC HDAC6 degrader 5 reduces HDAC6 levels through proteasome- and CRBN-dependent mechanisms (Pink: Target protein ligand (HY-174408), Target protein ligand + linker (HY-174409); Blue: Pomalidomide (HY-10984), Pomalidomide 4'-alkylC3-azide (HY-139341)) .
    PROTAC HDAC6 degrader 5

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