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Results for "

SHIP2

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-18686
    AS1949490
    1 Publications Verification

    		 Phosphatase Akt Metabolic Disease
    AS1949490 is a potent, orally active, selective SHIP2 phosphatase inhibitor with IC50 values of 0.34, 0.62, 13, >50, >50, and >50 µM for Mouse SHIP2, Human SHIP2, Human SHIP1, Human PTEN, Human synaptojanin, and Human myotubularin, respectively. AS1949490 increases the phosphorylation of Akt, glucose consumption and glucose uptake. AS1949490 activates intracellular insulin signalling pathways. AS1949490 can be used for research of diabetes [2].
    AS1949490
  • HY-18685
    CPDA

    		Phosphatase Metabolic Disease
    CPDA is a novel potent SH2 domain-containing inositol phosphatase 2 (SHIP2) inhibitor.
    CPDA
  • HY-112700
    SHIP2-IN-1

    		Phosphatase Neurological Disease
    SHIP2-IN-1 is a potent SHIP2 inhibitor, inhibits SHIP2 activity, with an IC50 of 2 μM. SHIP2-IN-1 blocks GSK3β activation by phosphorylation at the Ser9 residue. SHIP2-IN-1 is used in the research of Alzheimer’s disease .
    SHIP2-IN-1
  • HY-18284
    AS1938909

    		Akt GLUT Phosphatase Others
    AS1938909 is a compound that inhibits SHIP2 activity. It can selectively inhibit SHIP2, increase Akt phosphorylation, and regulate glucose metabolism. Its effect is related to upregulating GLUT1 gene expression.
    AS1938909
  • HY-RS06834
    INPPL1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    INPPL1 Human Pre-designed siRNA Set A contains three designed siRNAs for INPPL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    INPPL1 Human Pre-designed siRNA Set A
    INPPL1 Human Pre-designed siRNA Set A

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