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Trigenolline

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0414
    Trigonelline
    4 Publications Verification

    Trigenolline

    		 Endogenous Metabolite Ferroptosis Apoptosis HIV Bacterial Fungal Metabolic Disease Cancer
    Trigonelline is an alkaloid with potential antidiabetic activity that can be isolated from Trigonella foenum-graecum L or Leonurus artemisia. Trigonelline is a potent Nrf2 inhibitor that blocks Nrf2-dependent proteasome activity, thereby enhancing apoptosis in pancreatic cancer cells. Trigonelline also has anti-HSV-1, antibacterial, and antifungal activity and induces ferroptosis.
    Trigonelline

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