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UNC-6852

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-130708
    UNC6852
    2 Publications Verification

    		 Histone Methyltransferase PROTACs Cancer
    UNC6852 is a selective polycomb repressive complex 2 (PRC2) degrader based on PROTAC and contains an EED (embryonic ectoderm development) ligand and a von Hippel-Lindau ligand, with an IC50 of 247 nM for EED .
    <em>UNC6852</em>
  • HY-W004697
    Boc-GABA-OH

    		PROTAC Linkers Cancer
    Boc-GABA-OH is a PROTAC linker which can be used to synthesis UNC6852, an EED-targeted PROTAC .
    Boc-GABA-OH
  • HY-130979
    EED226-COOH

    		Ligands for Target Protein for PROTAC Cancer
    EED226-COOH is an EED226-derived ligand for target protein EED ligand for PROTAC, binds to a ligand for VHL via linker to form UNC6852 (HY-130708) to degrade PRC2 .
    EED226-COOH
  • HY-130711
    (S,R,S)-AHPC-C3-NH2

    VH032-C3-NH2

    		 E3 Ligase Ligand-Linker Conjugates Cancer
    (S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. (S,R,S)-AHPC-C3-NH2 can be used in the synthesis of a series of PROTACs, such as UNC6852 (HY-130708). UNC6852 is an EED-targeted bivalent chemical degrader .
    (S,R,S)-AHPC-C3-NH2
  • HY-130711A
    (S,R,S)-AHPC-C3-NH2 TFA

    VH032-C3-NH2 TFA

    		 E3 Ligase Ligand-Linker Conjugates Cancer
    (S,R,S)-AHPC-C3-NH2 TFA (VH032-C3-NH2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. (S,R,S)-AHPC-C3-NH2 can be used in the synthesis of a series of PROTACs, such as UNC6852 (HY-130708). UNC6852 is an EED-targeted bivalent chemical degrader .
    (S,R,S)-AHPC-C3-NH2 TFA
  • HY-130711C
    (S,R,S)-AHPC-C3-NH2 dihydrochloride

    VH032-C3-NH2 dihydrochloride

    		 E3 Ligase Ligand-Linker Conjugates Cancer
    (S,R,S)-AHPC-C3-NH2 (dihydrochloride) is the dihydrochloride form of (S,R,S)-AHPC-C3-NH2 (HY-130711). (S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. (S,R,S)-AHPC-C3-NH2 can be used in the synthesis of a series of PROTACs, such as UNC6852 (HY-130708). UNC6852 is an EED-targeted bivalent chemical degrader .
    (S,R,S)-AHPC-C3-NH2 dihydrochloride

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