1. PROTAC
  2. Ligand for Target Protein for PROTAC
  3. EED226-COOH

EED226-COOH 

Cat. No.: HY-130979
Handling Instructions

EED226-COOH is an EED226-derived ligand for target protein EED ligand for PROTAC, binds to a ligand for VHL via linker to form UNC6852 (HY-130708) to degrade PRC2.

For research use only. We do not sell to patients.

EED226-COOH Chemical Structure

EED226-COOH Chemical Structure

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Description

EED226-COOH is an EED226-derived ligand for target protein EED ligand for PROTAC, binds to a ligand for VHL via linker to form UNC6852 (HY-130708) to degrade PRC2[1].

IC50 & Target

EED[1]

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Molecular Weight

335.32

Formula

C₁₇H₁₃N₅O₃

SMILES

OC(C1=CC=C(C=C1)C2=CN=C(N3C2=NN=C3)NCC4=CC=CO4)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

EED226-COOHLigand for Target Protein for PROTACTarget Protein-binding MoietyLigandfortargetproteinEEDEED226UNC6852PROTACInhibitorinhibitorinhibit

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Product name:
EED226-COOH
Cat. No.:
HY-130979
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