1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugate
  3. (S,R,S)-AHPC-C3-NH2

(S,R,S)-AHPC-C3-NH2 (Synonyms: VH032-C3-NH2)

Cat. No.: HY-130711
Handling Instructions

(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. (S,R,S)-AHPC-C3-NH2 can be used in the synthesis of a series of PROTACs, such as UNC6852 (HY-130708). UNC6852 is an EED-targeted bivalent chemical degrader.

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(S,R,S)-AHPC-C3-NH2 Chemical Structure

(S,R,S)-AHPC-C3-NH2 Chemical Structure

CAS No. : 2361119-88-0

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Description

(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. (S,R,S)-AHPC-C3-NH2 can be used in the synthesis of a series of PROTACs, such as UNC6852 (HY-130708). UNC6852 is an EED-targeted bivalent chemical degrader[1].

IC50 & Target[1]

VHL

 

Molecular Weight

515.67

Formula

C₂₆H₃₇N₅O₄S

CAS No.

2361119-88-0

SMILES

NCCCC(N[[email protected]](C(N1[[email protected]@H](C[[email protected]](C1)O)C(NCC2=CC=C(C=C2)C3=C(N=CS3)C)=O)=O)C(C)(C)C)=O

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

(S,R,S)-AHPC-C3-NH2VH032-C3-NH2E3 Ligase Ligand-Linker ConjugateEED-TargetedVH032VHLPROTAClinkerInhibitorinhibitorinhibit

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(S,R,S)-AHPC-C3-NH2
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HY-130711
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