1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugate
  3. (S,R,S)-AHPC-C10-NH2

(S,R,S)-AHPC-C10-NH2 (Synonyms: VH032-C10-NH2)

Cat. No.: HY-129941
Handling Instructions

(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for BET-Targeted PROTAC.

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(S,R,S)-AHPC-C10-NH2 Chemical Structure

(S,R,S)-AHPC-C10-NH2 Chemical Structure

CAS No. : 2341796-74-3

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Description

(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for BET-Targeted PROTAC[1].

IC50 & Target[1]

VHL

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Molecular Weight

613.85

Formula

C₃₃H₅₁N₅O₄S

CAS No.

2341796-74-3

SMILES

NCCCCCCCCCCC(N[[email protected]@H](C(C)(C)C)C(N1[[email protected]](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[[email protected]@H](O)C1)=O)=O

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

(S,R,S)-AHPC-C10-NH2VH032-C10-NH2E3 Ligase Ligand-Linker ConjugatePROTACAHPCVHLBETInhibitorinhibitorinhibit

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(S,R,S)-AHPC-C10-NH2
Cat. No.:
HY-129941
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