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biotin protein ligase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (3) SNIPERs (1)
By Research Areas:	Cancer (1) Infection (3)

Inhibitors & Agonists

Recombinant Proteins

Targets Recommended: Ligands for E3 Ligase E3 Ligase Ligand-Linker Conjugates ByeTAC E1/E2/E3 Enzyme

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-115448

Bio-AMS	Bacterial	Infection
Bio-AMS is a potent bacterial **biotin protein ligase** inhibitor. Bio-AMS possesses selective activity against Mycobacterium tuberculosis (Mtb) and arrests fatty acid and lipid biosynthesis .

HY-115448A

Bio-AMS TFA	Bacterial	Infection
Bio-AMS (TFA) is a potent bacterial **biotin protein ligase** inhibitor. Bio-AMS (TFA) possesses selective activity against Mycobacterium tuberculosis (Mtb) and arrests fatty acid and lipid biosynthesis .

HY-168486

Biotin protein ligase-IN-1	Bacterial	Infection
Biotin protein ligase-IN-1 (Compound Bio-9) is an inhibitor of **biotin protein ligase (BPL) with a K_d** value of 7 nM. Biotin protein ligase-IN-1 exhibits antibacterial activity, with MIC values of 0.2 and 20 μM against Staphylococcus aureus (including MRSA and MSSA) and Mycobacterium tuberculosis, respectively .

HY-111879

Biotin-BS	SNIPERs	Cancer
Biotin-BS contains two different ligands, methyl-bestatin (MeBS) for cIAP1 and biotin, which are connected by linkers. MeBS as a ligand for cellular inhibitor of apoptosis protein 1 (cIAP1) ubiquitin ligase .

Species:	E.coli (1)
Tag:	His (2)
Source:	E. coli (2)

Cat. No.	Compare	상품명	Species	Source	Image

HY-P702154

	birA Protein, E. coli (His) birA; Bifunctional ligase/repressor BirA; biotin operon repressor; biotin--[acetyl-CoA-carboxylase] ligase; biotin--protein ligase; biotin-[acetyl-CoA carboxylase] synthetase	E.coli	E. coli
	The birA protein has the dual role of biotin ligase and biotin operon repressor. In the presence of ATP, it activates biotin to form the BirA-biotinyl-5'-adenylate complex. birA Protein, E. coli (His) is the recombinant E. coli-derived birA protein, expressed by E. coli , with N-6*His labeled tag.

HY-P703428

	birA Protein, B. subtilis (His) Bifunctional ligase/repressor BirA; biotin--[acetyl-CoA-carboxylase] ligase; 6.3.4.15; biotin--protein ligase; biotin-[acetyl-CoA carboxylase] synthetase; birA; Bacillus subtilis (strain 168); DNA-binding; ligase; Repressor	Others	E. coli
	birA Protein, B. subtilis (His) is the recombinant birA protein, expressed by E. coli, with His tag.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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