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calciprotein+particles

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-138822
    2,3-Diphospho-D-glyceric acid pentasodium salt

    2,3-DPG pentasodium salt

    		 Endogenous Metabolite Cardiovascular Disease
    2,3-Diphospho-D-glyceric acid (2,3-DPG) pentasodium salt is a hemoglobin binder and vascular calcification inhibitor that reduces the oxygen affinity of hemoglobin. 2,3-Diphospho-D-glyceric acid pentasodium salt also specifically delays the transformation of colloidal calciprotein particles into crystalline forms, thereby effectively inhibiting vascular smooth muscle cell calcification without affecting the normal formation of osteoid nodules in osteoblast-like cells. 2,3-Diphospho-D-glyceric acid pentasodium salt shows no cytotoxicity to tested cell lines and only weakly interferes with β-hematin formation mediated by glyceryl monopalmitate. 2,3-Diphospho-D-glyceric acid pentasodium salt can be used to study the pathological mechanisms of vascular calcification and malaria-related conditions .
    2,3-Diphospho-D-glyceric acid pentasodium salt

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