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dependency

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-136688
    MI-389

    		PROTACs Cancer
    MI-389 is a PROTAC translation termination factor GSPT1 degrader. MI-389 disrupts a target that is a shared dependency in different AML and ALL cell lines, and that MI-389 action is dependent on the CRL4 CRBN E3 ligase .
    MI-389
  • HY-155099
    FGH31

    		Dopamine Receptor Arrestin G Protein-coupled Receptor Kinase (GRK) Neurological Disease
    FGH31 (Compound 24) is a potent, selective, GRK2 dependency dopamine D4 agonist, with the Ki of 1.6 nM. FGH31 partial activates β- arrestin .
    FGH31
  • HY-106659
    SCH 900978

    NK-1 Antagonist 1

    		 Neurokinin Receptor Neurological Disease Endocrinology
    SCH 900978 (NK-1 Antagonist 1) is an antagonist of NK-1 receptor, used in the research of NK-1 related diseases and conditions such as cough, overactive bladder, alcohol dependency and depression .
    SCH 900978
  • HY-109147
    Imnopitant

    		Neurokinin Receptor Neurological Disease Endocrinology
    Imnopitant is a NK1 receptor antagonist (WO2020132716, compound 1) .
    Imnopitant
  • HY-153847
    RNA Aptamer Mango ΙΙ sodium

    		Others Others
    RNA Aptamer Mango Ⅱ (sodium) has an exceptionally high affinity to TO1-biotin (a thiazole orange derivative fluorophore), and can be used to visualize RNA expression or localization in live cells. Compared to the original Mango I aptamer, RNA Aptamer Mango Ⅱ (sodium) has markedly improved fluorescent properties, binding affinities, and salt dependencies.
    RNA Aptamer Mango ΙΙ sodium
  • HY-153848
    RNA Aptamer Mango Ⅳ sodium

    		Others Others
    RNA Aptamer Mango Ⅳ (sodium) has an exceptionally high affinity to TO1-biotin (a thiazole orange derivative fluorophore), and can be used to visualize RNA expression or localization in live cells. Compared to the original Mango I aptamer, RNA Aptamer Mango Ⅳ has markedly improved fluorescent properties, binding affinities, and salt dependencies.
    RNA Aptamer Mango Ⅳ sodium
  • HY-153849
    RNA Aptamer Mango Ⅲ sodium

    		Others Others
    RNA Aptamer Mango Ⅲ (sodium) has an exceptionally high affinity to TO1-biotin (a thiazole orange derivative fluorophore), and can be used to visualize RNA expression or localization in live cells. Compared to the original Mango I aptamer, RNA Aptamer Mango Ⅲ has markedly improved fluorescent properties, binding affinities, and salt dependencies.
    RNA Aptamer Mango Ⅲ sodium

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