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exoribonuclease XRN1 inhibitor

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-173593

    Small Interfering RNA (siRNA) Cancer
    Adenosine-3',5'-bisphosphate is an exoribonuclease XRN1 inhibitor with an IC50 of 36 nM, a KD of 12 nM, and a KD of 14 nM against human XRN2. Adenosine-3',5'-bisphosphate binds to the bimetallic active site of human XRN1, and also binds potently to human XRN2 via its conserved bimetallic active site. Adenosine-3',5'-bisphosphate can be used in research related to non-small cell lung cancer .
    Adenosine-3',5'-bisphosphate

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