Adenosine-3',5'-bisphosphate
Adenosine-3',5'-bisphosphate is an exoribonuclease XRN1 inhibitor with an IC50 of 36 nM, a KD of 12 nM, and a KD of 14 nM against human XRN2. Adenosine-3',5'-bisphosphate binds to the bimetallic active site of human XRN1, and also binds potently to human XRN2 via its conserved bimetallic active site. Adenosine-3',5'-bisphosphate can be used in research related to non-small cell lung cancer.
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- CAS No.: 1053-73-2
- Formule: C10H15N5O10P2
- Masse moléculaire:427.20
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
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Help & FAQs
Activité biologique
Description
In Vitro
Adenosine-3',5'-bisphosphate binds to the bimetallic active site of the purified human hXRN1x catalytic domain, forming specific interactions with protein residues and magnesium ions[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1053-73-2
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Masse moléculaire 427.20
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Formule C10H15N5O10P2
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SMILES
O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(O)=O)O[C@H]1N2C3=NC=NC(N)=C3N=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Adenosine-3',5'-bisphosphate Related Classifications
HY-173593 Related Classifications
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