Adenosine-3',5'-bisphosphate
Adenosine-3',5'-bisphosphate is an exoribonuclease XRN1 inhibitor with an IC50 of 36 nM, a KD of 12 nM, and a KD of 14 nM against human XRN2. Adenosine-3',5'-bisphosphate binds to the bimetallic active site of human XRN1, and also binds potently to human XRN2 via its conserved bimetallic active site. Adenosine-3',5'-bisphosphate can be used in research related to non-small cell lung cancer.
For research use only. We do not sell to patients.
- CAS No.: 1053-73-2
- Formula: C10H15N5O10P2
- Molecular Weight:427.20
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Adenosine-3',5'-bisphosphate binds to the bimetallic active site of the purified human hXRN1x catalytic domain, forming specific interactions with protein residues and magnesium ions[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 1053-73-2
-
Molecular Weight 427.20
-
Formula C10H15N5O10P2
-
SMILES
O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(O)=O)O[C@H]1N2C3=NC=NC(N)=C3N=C2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Adenosine-3',5'-bisphosphate Related Classifications
HY-173593 Related Classifications
Powered by Bioz