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malignant+melanoma+cells

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Caspase (1) CDK (1) Checkpoint Kinase (Chk) (1) PROTACs (2) Reference Standards (1)
By Research Areas:	Cancer (4)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Picrocrocin	Apoptosis	Cancer
Picrocrocin, an apocarotenoid found in Saffron. Picrocrocin shows anticancer effect. Picrocrocin exhibits growth inhibitory effects against SKMEL-2 human malignant melanoma cells .

PROTAC Chk1 degrader-1	PROTACs Checkpoint Kinase (Chk)	Cancer
PROTAC Chk1 degrader-1 is a Chk1-targeting PROTAC.PROTAC Chk1 degrader-1 recruits the Cereblon E3 ligase to induce ubiquitination and proteasomal degradation of Chk1.PROTAC Chk1 degrader-1 exhibits Chk1 degradation activity in malignant melanoma cells without showing a hook effect.PROTAC Chk1 degrader-1 can be used for the research of malignant melanoma .

Picrocrocin (Standard)	Reference Standards Apoptosis	Cancer
Picrocrocin (Standard) is the analytical standard of Picrocrocin. This product is intended for research and analytical applications. Picrocrocin, an apocarotenoid found in Saffron. Picrocrocin shows anticancer effect. Picrocrocin exhibits growth inhibitory effects against SKMEL-2 human malignant melanoma cells .

PROTAC CDK2/4/6 Degrader-2	PROTACs CDK Caspase	Cancer
PROTAC CDK2/4/6 Degrader-2 is a CDK2/4/6 PROTAC degrader. PROTAC CDK2/4/6 Degrader-2. PROTAC CDK2/4/6 Degrader-2 can be converted into the prodrug PROTAC CDK2/4/6 Degrader-1 (HY-171826) through a one-step reaction with chloromethyl pivalate. PROTAC CDK2/4/6 Degrader-2 degrades CDK2/4/6 and their complex in malignant melanomas cells. PROTAC CDK2/4/6 Degrader-2 induces cell cycle arrest and cell apoptosis in various cancer cells, in particular for melanomas. PROTAC CDK2/4/6 Degrader-2 can be used for malignant melanomas research .

Picrocrocin	Classification of Application Fields Ketones, Aldehydes, Acids Lridaceae Plants Crocus sativus L. Disease Research Fields Source Classification Cancer	Apoptosis
Picrocrocin, an apocarotenoid found in Saffron. Picrocrocin shows anticancer effect. Picrocrocin exhibits growth inhibitory effects against SKMEL-2 human malignant melanoma cells .

Picrocrocin (Standard)	Structural Classification Ketones, Aldehydes, Acids Lridaceae Plants Crocus sativus L. Source Classification	Reference Standards Apoptosis
Picrocrocin (Standard) is the analytical standard of Picrocrocin. This product is intended for research and analytical applications. Picrocrocin, an apocarotenoid found in Saffron. Picrocrocin shows anticancer effect. Picrocrocin exhibits growth inhibitory effects against SKMEL-2 human malignant melanoma cells .

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