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nonionic triblock copolymer

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By Targets:	Biochemical Assay Reagents (3)
By Research Areas:	Infection (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D1005I

Poloxamer L61	Biochemical Assay Reagents	Others
Poloxamer L61 is a non-ionic triblock copolymer surfactant. Poloxamer L61 effectively achieves intracellular molecular delivery to cancer cells during photoacoustic molecular delivery, and maintains cell viability by promoting cell membrane resealing, thus avoiding irreversible damage caused by laser-induced membrane permeabilization. Poloxamer L61 is a key component of SP1017, a compound related to gene therapy, which regulates the interaction between DNA and extracellular matrix as well as cellular uptake, and significantly enhances the distribution and bioavailability of plasmid DNA in skeletal muscle. Poloxamer L61 can be used in studies on local or systemic therapeutic protein production .

HY-D1005A5

Poloxamer 123 (L43) PEG-PPG-PEG, 1850 (Average)	Biochemical Assay Reagents	Others
Poloxamer 123 (L43) (PEG-PPG-PEG, average molecular weight 1850) is a nonionic triblock copolymer of polyoxyethylene-polyoxypropylene-polyoxyethylene with an average molecular weight of 1850. Poloxamer 123 L43 can be used as a surfactant, emulsifier, and solubilizer in cosmetics .

HY-D1005A4

Poloxamer 122 (L42) PEG-PPG-PEG, 1630 (Average)	Biochemical Assay Reagents	Infection
Poloxamer 122 L42 (PEG-PPG-PEG, 1630 (Average)) is a synthetic nonionic triblock copolymer composed of polyoxyethylene-polyoxypropylene, with emulsifying and wetting properties. Poloxamer 122 L42 forms large spherical aggregates in aqueous solutions near its cloud point,. Poloxamer 122 L42 can form thermoreversible hydrogels, and is also used in research related to serving as a drug delivery carrier in the fields of food additives, cosmetics, pharmaceutical preparations and tissue engineering .

Cat. No.	Product Name	Type

HY-D1005I

Poloxamer L61	Biochemical Assay Reagents
Poloxamer L61 is a non-ionic triblock copolymer surfactant. Poloxamer L61 effectively achieves intracellular molecular delivery to cancer cells during photoacoustic molecular delivery, and maintains cell viability by promoting cell membrane resealing, thus avoiding irreversible damage caused by laser-induced membrane permeabilization. Poloxamer L61 is a key component of SP1017, a compound related to gene therapy, which regulates the interaction between DNA and extracellular matrix as well as cellular uptake, and significantly enhances the distribution and bioavailability of plasmid DNA in skeletal muscle. Poloxamer L61 can be used in studies on local or systemic therapeutic protein production .

Poloxamer L61

Biochemical Assay Reagents

Poloxamer L61 is a non-ionic triblock copolymer surfactant. Poloxamer L61 effectively achieves intracellular molecular delivery to cancer cells during photoacoustic molecular delivery, and maintains cell viability by promoting cell membrane resealing, thus avoiding irreversible damage caused by laser-induced membrane permeabilization. Poloxamer L61 is a key component of SP1017, a compound related to gene therapy, which regulates the interaction between DNA and extracellular matrix as well as cellular uptake, and significantly enhances the distribution and bioavailability of plasmid DNA in skeletal muscle. Poloxamer L61 can be used in studies on local or systemic therapeutic protein production .

HY-D1005A5

Poloxamer 123 (L43) PEG-PPG-PEG, 1850 (Average)	Biochemical Assay Reagents
Poloxamer 123 (L43) (PEG-PPG-PEG, average molecular weight 1850) is a nonionic triblock copolymer of polyoxyethylene-polyoxypropylene-polyoxyethylene with an average molecular weight of 1850. Poloxamer 123 L43 can be used as a surfactant, emulsifier, and solubilizer in cosmetics .

HY-D1005A4

Poloxamer 122 (L42) PEG-PPG-PEG, 1630 (Average)	Biochemical Assay Reagents
Poloxamer 122 L42 (PEG-PPG-PEG, 1630 (Average)) is a synthetic nonionic triblock copolymer composed of polyoxyethylene-polyoxypropylene, with emulsifying and wetting properties. Poloxamer 122 L42 forms large spherical aggregates in aqueous solutions near its cloud point,. Poloxamer 122 L42 can form thermoreversible hydrogels, and is also used in research related to serving as a drug delivery carrier in the fields of food additives, cosmetics, pharmaceutical preparations and tissue engineering .

Poloxamer 122 (L42)

PEG-PPG-PEG, 1630 (Average)

Biochemical Assay Reagents

Poloxamer 122 L42 (PEG-PPG-PEG, 1630 (Average)) is a synthetic nonionic triblock copolymer composed of polyoxyethylene-polyoxypropylene, with emulsifying and wetting properties. Poloxamer 122 L42 forms large spherical aggregates in aqueous solutions near its cloud point,. Poloxamer 122 L42 can form thermoreversible hydrogels, and is also used in research related to serving as a drug delivery carrier in the fields of food additives, cosmetics, pharmaceutical preparations and tissue engineering .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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