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thioglycoside

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Derivative (1) Insecticide (1)
By Research Areas:	Endocrinology (1)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N10348

Progoitrin	Others Drug Derivative	Endocrinology
Progoitrin is a sulfur-containing glucosinolate, as well as a naturally occurring orally active thioglycoside. Progoitrin acts as a hepatotoxin and antithyroid agent. Progoitrin is quantitatively converted to goitrin in vivo, including via a gastrointestinal hydrolysis pathway that does not require exogenous myrosinase, thereby blocking the organification of iodine in the thyroid gland and inhibiting the uptake and accumulation of radioactive iodine. Progoitrin can be used in studies related to Graves' disease .

HY-147701

OfHex1-IN-1	Insecticide	Others
OfHex1-IN-1 (compound 11c) is a potent and selective OfHex1 (β-N-acetylhexosaminidase from Ostrinia furnacalis) inhibitor, with an IC₅₀ of 28.1 μM and a K_i of 25.6 μM. OfHex1-IN-1 can be used for OfHex1-related green pesticides research .

Cat. No.	Product Name

HY-L042

Glycoside Compound Library	894 compounds
Glycosides are compounds in which a sugar group is bonded through its anomeric carbon to another group via a glycosidic bond. Many biologically active compounds are glycosides. Glycosides comprise several important classes of compounds such as hormones, sweeteners, alkaloids, flavonoids, antibiotics, etc. The glycosidic residue can be crucial for their activity or can only improve pharmacokinetic parameters. Glycosides, which exhibit anti-inflammatory, anti-infection, anti-cancer and anti-oxidative properties, play numerous important roles in living organisms, such as streptomycin, as an aminoglycoside antibiotic, has anti-infection activity. Anthracyclines possess good antibacterial and anti-cancer activities. MCE Glycoside Compound Library contains a unique collection of 894 glycoside compounds and is a useful tool to discovery glycoside drugs.

Glycoside Compound Library

894 compounds

Glycosides are compounds in which a sugar group is bonded through its anomeric carbon to another group via a glycosidic bond. Many biologically active compounds are glycosides. Glycosides comprise several important classes of compounds such as hormones, sweeteners, alkaloids, flavonoids, antibiotics, etc. The glycosidic residue can be crucial for their activity or can only improve pharmacokinetic parameters. Glycosides, which exhibit anti-inflammatory, anti-infection, anti-cancer and anti-oxidative properties, play numerous important roles in living organisms, such as streptomycin, as an aminoglycoside antibiotic, has anti-infection activity. Anthracyclines possess good antibacterial and anti-cancer activities.

MCE Glycoside Compound Library contains a unique collection of 894 glycoside compounds and is a useful tool to discovery glycoside drugs.

Progoitrin	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Glucosinolates Plants Brassica napus var. napobrassica (L.) Rchb. Brassicaceae Disease Research Fields Endocrinology Source Classification	Others Drug Derivative
Progoitrin is a sulfur-containing glucosinolate, as well as a naturally occurring orally active thioglycoside. Progoitrin acts as a hepatotoxin and antithyroid agent. Progoitrin is quantitatively converted to goitrin in vivo, including via a gastrointestinal hydrolysis pathway that does not require exogenous myrosinase, thereby blocking the organification of iodine in the thyroid gland and inhibiting the uptake and accumulation of radioactive iodine. Progoitrin can be used in studies related to Graves' disease .

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thioglycoside

Inhibitors & Agonists

Screening Libraries

NaturalProducts

Natural
Products