2. GPCR/G Protein Neuronal Signaling
  3. Neurokinin Receptor
  4. Septide

Septide  (Synonyms: (Pyr6,Pro9)-Substance P)

Cat. No.: HY-P2000 Pureza: 98.97%
COA
SDS
Instrucciones de manejo Technical Support

Septide ((Pyr6,Pro9)-Substance P) is a potent NK1 receptor agonist with a Kd value of 0.55 nM.

Para uso exclusivo en investigación. No vendemos a pacientes.

Síntesis de péptidos personalizados

Septide

Septide Estructura química

No. CAS : 79775-19-2

Tamaño Precio Stock Cantidad
5 mg En stock
10 mg En stock
50 mg   Obtener un presupuesto  
100 mg   Obtener un presupuesto  

* Seleccione Cantidad antes de agregar artículos.

This product is a controlled substance and not for sale in your territory.

Revisión del cliente

Based on 1 Customer Validation

Septide Related Antibodies

Top Publications Citing Use of Products

Ver todos los productos específicos de isoformas Neurokinin Receptor:

Ver todas las isoformas
NK1R NK2R NK3R

  • Actividad biológica

  • Pureza y Documentación

  • Referencias

  • Revisión del cliente

Descripciòn

Septide ((Pyr6,Pro9)-Substance P) is a potent NK1 receptor agonist with a Kd value of 0.55 nM[1].

IC50 & Target

Kd: 0.55 ± 0.03 nM (NK1 receptor)[1]
In Vitro

Septide increases inositol phosphate levels (4-6-fold) in NK1 receptor expressed CHO cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Septide Related Antibodies
Peso molecular

763.95

Fòrmula

C39H53N7O7S
No. CAS
Appearance

Solid

Color

White to off-white

Sequence Shortening

Glp-FFPLM-NH2
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad
In Vitro: 

DMSO : 100 mg/mL (130.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3090 mL 6.5449 mL 13.0899 mL
5 mM 0.2618 mL 1.3090 mL 2.6180 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3090 mL 6.5449 mL 13.0899 mL 32.7247 mL
5 mM 0.2618 mL 1.3090 mL 2.6180 mL 6.5449 mL
10 mM 0.1309 mL 0.6545 mL 1.3090 mL 3.2725 mL
15 mM 0.0873 mL 0.4363 mL 0.8727 mL 2.1816 mL
20 mM 0.0654 mL 0.3272 mL 0.6545 mL 1.6362 mL
25 mM 0.0524 mL 0.2618 mL 0.5236 mL 1.3090 mL
30 mM 0.0436 mL 0.2182 mL 0.4363 mL 1.0908 mL
40 mM 0.0327 mL 0.1636 mL 0.3272 mL 0.8181 mL
50 mM 0.0262 mL 0.1309 mL 0.2618 mL 0.6545 mL
60 mM 0.0218 mL 0.1091 mL 0.2182 mL 0.5454 mL
80 mM 0.0164 mL 0.0818 mL 0.1636 mL 0.4091 mL
100 mM 0.0131 mL 0.0654 mL 0.1309 mL 0.3272 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Septide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Septide79775-19-2(Pyr6,Pro9)-Substance PNeurokinin ReceptorNK receptorTachykinin receptorNK1 receptorCHOInhibitorinhibitorinhibit

Productos vistos recientemente:

Consulta en línea

Your information is safe with us. * Required Fields.

Nombre del producto

  

Requested Quantity *

Nombre del solicitante *

 

Saludo

Direcciòn del E-mail *

 

Número de teléfono *

Department

 

Nombre de la Organizaciòn *

City

Provincia

Country or Region *

      

Observaciones

Consulta para venta a granel

Inquiry Information

Nombre del producto:
Septide
Cat. No.:
HY-P2000
Cantidad:
MCE Japan Authorized Agent:

Revisión del cliente

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Nombre del producto

  

Lot #

Nombre del solicitante *

 

Direcciòn del E-mail *

Número de teléfono

 

Department *

Nombre de la Organizaciòn *

 

Country or Region *

Observaciones

SAFETY DATA SHEET (SDS)

English - EN (252 KB) Français - FR (252 KB) Deutsch - DE (252 KB) Norwegian - NO (252 KB) Español - ES (252 KB) Swedish - SV (252 KB) Italian - IT (252 KB) Korean - KR (252 KB) Portuguese - PT (252 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.