Sodium lauroyl glutamate 

Sodium lauroyl glutamate is an anionic amino acid surfactant. Sodium lauroyl glutamate has the irritant contact dermatitis potential, and possible anti-irritating potential in a surfactant mixture on human skin^[1].

Sodium lauroyl glutamate (1% w/w, 1 h) is a mild surfactant and is mainly used in cleaning products. Sodium lauroyl glutamate has a pH value of 5.41, exhibiting a low irritation to the nude mouse skin^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

351.41

C₁₇H₃₀NNaO₅

29923-31-7

Solid

White to off-white

O=C(O)CC[C@@H](C(O[Na])=O)NC(CCCCCCCCCCC)=O

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

• [1]. Lee CH, et al. Effect of surfactant mixtures on irritant contact dermatitis potential in man: sodium lauroyl glutamate and sodium lauryl sulphate. Contact Dermatitis. 1994 Apr;30(4):205-9.  [Content Brief]

  [2]. Okasaka M, et al., Evaluation of anionic surfactants effects on the skin barrier function based on skin permeability. Pharm Dev Technol. 2019 Jan;24(1):99-104.  [Content Brief]