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  4. Solutol HS-15

Solutol HS-15  (Synonyms: Polyethylene glycol 12-hydroxystearate)

製品番号: HY-Y1893
COA 取扱説明書 Technical Support

Solutol HS-15, a Macrogol 15 hydroxy stearate, is a permeability enhancer.

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Solutol HS-15

Solutol HS-15 構造式

CAS 番号 : 61909-81-7

容量 価格（税別） 在庫状況 数量
10 g $50 在庫あり
50 g $80 在庫あり
100 g $135 在庫あり
500 g $500 在庫あり
> 100 g   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Based on 21 publication(s) in Google Scholar

Solutol HS-15 関連抗体

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  • 純度とドキュメンテーション

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製品説明

Solutol HS-15, a Macrogol 15 hydroxy stearate, is a permeability enhancer[1].

体外実験

Solutol HS-15 is used to increase the aqueous solubility of Biopharmaceutical Classification System (BCS) Class 2 and 4 lipophilic molecules. Solutol HS-15 has shown an enhancement in permeability of medium sized biological drugs across epithelia[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Solutol HS-15 関連抗体
分子式

(C2H4O)nC18H36O3
CAS 番号
Appearance

Oil

Color

Colorless to off-white

SMILES

CCCCCCC(O)CCCCCCCCCCC(OCCO)=O.[n]
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

4°C, sealed storage, away from moisture

*In solvent : sealed storage, away from moisture
溶剤 & 溶解度
体外: 

Ethanol : 100 mg/mL (Need ultrasonic)

H2O : 25 mg/mL (Need ultrasonic)

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

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体積 （開始）

V1

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濃度 （終了）

C2

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体積 （終了）

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション

COA (241 KB)

取扱説明書 (2659 KB)
参考文献
細胞実験
[1]

For both MTS and LDH cell viability assays, cells are seeded at a density of 1×104 cells on 96-well plates and cultured for a minimum of 24 h. Solutol HS-15 (in 25 mM HBSS:HEPES, pH 7.4) solutions are applied at concentrations above and below the critical micelle concentration (CMC) (0.01 mM to 20 mM) and cytotoxicity is determined using the MTS and LDH assays. 25 mM HBSS:HEPES is used as a negative control and Triton-X 100 (3 mM) as a positive control. Following 3 h incubation, the MTS reagent in media and LDH working solution are added to the cells and the cells are incubated for a further 3 h at 37°C[1].

MedChemExpress (MCE) はこれらの方法の精度を確認していません。 こちらは参照専用です。
参考文献
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Solutol HS-15 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Solutol HS-1561909-81-7Polyethylene glycol 12-hydroxystearateSolutol HS15Solutol HS 15Biochemical Assay ReagentsSolutolHS-15 Kolliphor HS 1570142-34-6Inhibitorinhibitorinhibit

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製品番号:
HY-Y1893
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