Stearoyl glutamic acid sodium  (Synonyms: Sodium stearoyl glutamate)

Sodium stearoyl glutamate is a sodium salt of monocarboxylic acid anionic surfactant, which serves as a chelating agent, skin sensitizer and anionic co-emulsifier^[1][2].

Sodium stearoyl glutamate (0.6% w/w), used as an anionic co-emulsifier in FB1 O/W emulsions, increases apparent viscosity, reduces particle size, enhances particle size uniformity, and improves long-term physical stability under different storage temperatures^[3].
Sodium stearoyl glutamate (0.6% w/w) exhibits excellent preservative efficacy in FB1 emulsion. It completely eliminates all tested bacteria, yeasts and fungi within 7 days after inoculation, and maintains microbial sterility until day 28^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

435.57

C₂₃H₄₂NNaO₅

38517-23-6

Solid

CCCCCCCCCCCCCCCCCC(N[C@H](C(O)=O)CCC(O[Na])=O)=O

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

• [1]. Nazir I, et al. Self-emulsifying drug delivery systems: Impact of stability of hydrophobic ion pairs on drug release. Int J Pharm. 2019;561:197-205.  [Content Brief]

  [2]. Pralong P, et al. Sodium stearoyl glutamate: Another amino acid alkyl amide sensitizer in cosmetics. Contact Dermatitis. 2022 Nov;87(5):453-454.  [Content Brief]

  [3]. Gulherme Carneiro Leal, et al. Development, characterization, and evaluation by cutaneous bioengineering of a naturalemusion, to provide a standardized vehicle base for topical compounded preparations. Research, Society and Development[S. 1.], v.11, n.16, p.e509111638290, 2022.