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  4. Streptavidin

ストレプトアビジン  (Synonyms: Streptavidin)

製品番号: HY-P3152 純度: 98.5%
COA 取扱説明書 Technical Support

Streptavidin is a ~60 kDa homotetramer. Streptavidin binds four molecules of biotin with the highest affinity. The binding affinity of biotin to streptavidin is one of the highest reported for a non-covalent interaction to date, with a KD ~0.01 pM. Streptavidin has an immunosuppressive role.
This product is a Streptavidin protein recombinantly expressed in an E. coli expression system.

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Streptavidin

ストレプトアビジン 構造式

CAS 番号 : 9013-20-1

容量 価格（税別） 在庫状況 数量
1 mg $50 在庫あり
5 mg $160 在庫あり
10 mg $240 在庫あり
25 mg $480 在庫あり
50 mg $720 在庫あり
100 mg $1100 在庫あり
200 mg   お問い合わせ  
500 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 5 publication(s) in Google Scholar

ストレプトアビジン 関連抗体

Top Publications Citing Use of Products

  • 生物活性

  • 純度とドキュメンテーション

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製品説明

Streptavidin is a ~60 kDa homotetramer. Streptavidin binds four molecules of biotin with the highest affinity. The binding affinity of biotin to streptavidin is one of the highest reported for a non-covalent interaction to date, with a KD ~0.01 pM[1]. Streptavidin has an immunosuppressive role[2].
This product is a Streptavidin protein recombinantly expressed in an E. coli expression system.

体外実験

Streptavidin (2-200 μg/mL) significantly suppresses the proliferation of Lewis T cells to WF by 76%-83% compared with untreated responders[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ストレプトアビジン 関連抗体

Cell Viability Assay[1]

Cell Line: Lewis T cells
Concentration: 2-200 μg/mL
Incubation Time:
Result: Inhibited the proliferation of Lewis T cells to WF stimulators by 76%-83% compared with untreated responders, lower concentrations of 0.1 and 0.2 μg/mL did not significantly inhibit T-cell proliferation.
体内実験

Streptavidin (8-80 mg/kg) treatment is effective in prolonging rat cardiac allografts in the high-responder WF-to-Lewis combination[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Lewis rats[2]
Dosage: 8, 12, 20, 40, 60, or 80 mg/kg
Administration: Administered IP for 5 consecutive days after transplantation was combined with a single dose of 0.5 mL antilymphocyte serum (ALS) on day 0
Result: Prolonged cardiac allograft survival from MST of 7.3±0.5 and 8.4±0.5 days in naive and ALS-treated controls, respectively, to 15±1, 20±3, 16±3, 17±3, and 23±2 days, respectively.
CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

[Streptavidin]
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外: 

H2O : 100 mg/mL (Need ultrasonic)

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This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
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純度とドキュメンテーション

純度: ≥99.0%

COA (230 KB)

取扱説明書 (2659 KB)
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Streptavidin Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Streptavidin9013-20-1Biochemical Assay Reagentsbiotin-binding proteinversatile affinity tagvisualize biotinInhibitorinhibitorinhibit

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