2. Others Protein Tyrosine Kinase/RTK Apoptosis
  3. Reference Standards FLT3 c-Kit PDGFR Apoptosis
  4. Tandutinib hydrochloride (Standard)

Tandutinib hydrochloride (Standard)  (Synonyms: MLN518 hydrochloride (Standard); CT53518 hydrochloride (Standard))

Art. -Nr.: HY-10202AR Reinheit: 98%
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Tandutinib (hydrochloride) (Standard) is the analytical standard of Tandutinib (hydrochloride). This product is intended for research and analytical applications. Tandutinib hydrochloride (MLN518 hydrochloride) is a potent and selective inhibitor of the FLT3 with an IC50 of 0.22 μM, and also inhibits c-Kit and PDGFR with IC50s of 0.17 μM and 0.20 μM, respectively. Tandutinib hydrochloride can be used for acute myelogenous leukemia (AML). Tandutinib hydrochloride has the ability to cross the blood-brain barrier.

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Tandutinib hydrochloride (Standard)

Tandutinib hydrochloride (Standard) Chemische Struktur

CAS. Nr. : 2438900-70-8

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Information

Tandutinib (hydrochloride) (Standard) is the analytical standard of Tandutinib (hydrochloride). This product is intended for research and analytical applications. Tandutinib hydrochloride (MLN518 hydrochloride) is a potent and selective inhibitor of the FLT3 with an IC50 of 0.22 μM, and also inhibits c-Kit and PDGFR with IC50s of 0.17 μM and 0.20 μM, respectively. Tandutinib hydrochloride can be used for acute myelogenous leukemia (AML). Tandutinib hydrochloride has the ability to cross the blood-brain barrier.

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molekulargewicht

599.16

Formel

C31H43ClN6O4
CAS. Nr.
SMILES

O=C(N1CCN(C2=C(C(C=C3OCCCN4CCCCC4)=NC=N2)C=C3OC)CC1)NC5=CC=C(OC(C)C)C=C5.Cl
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
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Tandutinib hydrochloride (Standard) Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tandutinib hydrochloride (Standard)2438900-70-8MLN518 hydrochloride (Standard) CT53518 hydrochloride (Standard)Reference StandardsFLT3c-KitPDGFRApoptosisCluster of differentiation antigen 135CD135Fms like tyrosine kinase 3SCFRCD117Platelet-derived growth factor receptorAcutemyelogenousleukemiaautophosphorylationMAPPI3FLT3-ITDblood-brainbarrierInhibitorinhibitorinhibit

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