2. Metabolic Enzyme/Protease
  3. Ser/Thr Protease
  4. Tenecteplase

Tenecteplase (TNK-tPA) is a modified tissue plasminogen activator. Tenecteplase is a recombinant human tissue plasminogen activator (rt-PA) that has been bioengineered to produce mutations in three gene loci. Tenecteplase (TNK-tPA) can be used in the study of acute ischemic stroke.

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Tenecteplase

Tenecteplase 화학구조

CAS No. : 191588-94-0

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100 μg 해외재고보유

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Tenecteplase Related Antibodies

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제품 설명

Tenecteplase (TNK-tPA) is a modified tissue plasminogen activator. Tenecteplase is a recombinant human tissue plasminogen activator (rt-PA) that has been bioengineered to produce mutations in three gene loci. Tenecteplase (TNK-tPA) can be used in the study of acute ischemic stroke[1][2].

In Vitro

Tenecteplase exhibits relatively slight cytotoxicity to neuronal cells compared to its parent compound Alteplase (HY-108865)[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Tenecteplase Related Antibodies
In Vivo

Tenecteplase (0.25-2.5 mg/kg, iv, single dose) reduces infarct volume when administered in the first 30 minutes, ameliorates thrombin-induced ischemic thromboembolism in mouse model[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Mouse ischemic thromboembolic models[3].
Dosage: 0.25-2.5 mg/kg
Administration: iv, single dose
Result: Reduced infarct volume.
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Tenecteplase]
선적

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보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서

SDS (251 KB)

COA (242 KB)

Handling Instructions (2659 KB)
References
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Tenecteplase Related Classifications

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  • 농도 희석 계산기

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tenecteplase191588-94-0TNK-tPASer/Thr ProteaseSerine proteasesSerine endopeptidasesThreonine proteasestenecteplaseischaemic strokeInhibitorinhibitorinhibit

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상품명:
Tenecteplase
Cat. No.:
HY-108845
수량:
MCE Japan Authorized Agent:

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