1. Inhibitory Antibodies
  2. Tezepelumab

Tezepelumab  (Synonyms: AMG 157; MEDI 19929; Tezepelumab-ekko)

Cat. No.: HY-P99366 Purity: ≥95.0%
COA

Tezepelumab (AMG 157) is human monoclonal antibody (IgG2λ) that binds specifically to TSLP, blocking it from interacting with its heterodimeric receptor. Tezepelumab can be used for the research of severe, uncontrolled asthma.

For research use only. We do not sell to patients.

Tezepelumab Chemical Structure

Tezepelumab Chemical Structure

CAS No. : 1572943-04-4

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Description

Tezepelumab (AMG 157) is human monoclonal antibody (IgG2λ) that binds specifically to TSLP, blocking it from interacting with its heterodimeric receptor. Tezepelumab can be used for the research of severe, uncontrolled asthma[1].

IC50 & Target

TSLP[1]

In Vitro

Tezepelumab blocks thymic stromal lymphopoietin, an epithelial-cell-derived cytokine implicated in the pathogenesis of asthma[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Tezepelumab]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Purity: ≥95.0%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Tezepelumab
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HY-P99366
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