WAY-639872

Cat. No.: HY-149741 Purity: ≥98.0%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

WAY-639872 is an active molecule.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

WAY-639872 화학구조

CAS No. : 796119-18-1

사이즈	재고	수량
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	견적 받기
100 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

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제품 설명

WAY-639872 is an active molecule.

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	IC₅₀	0.031 μM Compound: 1	Inhibition of slow inactivated human NaV1.7 expressed in HEK293 cells at -20 mV holding potential after 5 mins by IonWorks electrophysiology method Inhibition of slow inactivated human NaV1.7 expressed in HEK293 cells at -20 mV holding potential after 5 mins by IonWorks electrophysiology method	[PMID: 28684121]
HEK293	IC₅₀	0.98 μM Compound: 1	Inhibition of human NaV1.5 expressed in HEK293 cells at -50 mV holding potential after 3 to 5 mins by PatchXpress automated electrophysiology method Inhibition of human NaV1.5 expressed in HEK293 cells at -50 mV holding potential after 3 to 5 mins by PatchXpress automated electrophysiology method	[PMID: 28684121]
HEK293	IC₅₀	10 μM Compound: 1	Inhibition of human NaV1.7 expressed in HEK293 cells at -125 mV holding potential yielding 20 to 50% inactivation after 3 to 5 mins by PatchXpress automated electrophysiology method Inhibition of human NaV1.7 expressed in HEK293 cells at -125 mV holding potential yielding 20 to 50% inactivation after 3 to 5 mins by PatchXpress automated electrophysiology method	[PMID: 28684121]

분자량

363.41

화학식

C₂₁H₂₁N₃O₃

CAS No.

796119-18-1

Appearance

Solid

Color

Light yellow to orange

SMILES

O=C(COC1=C2N=CC=CC2=CC=C1)NC3=C(N4CCOCC4)C=CC=C3

선적

Room temperature in continental US; may vary elsewhere.

보관

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

용액&용해도

In Vitro:

DMSO : 100 mg/mL (275.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.7517 mL	13.7586 mL	27.5171 mL
5 mM	0.5503 mL	2.7517 mL	5.5034 mL
10 mM	0.2752 mL	1.3759 mL	2.7517 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: ≥98.0%

Select Batch:

Data Sheet (246 KB) SDS (251 KB)

COA (253 KB) HNMR (419 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.7517 mL	13.7586 mL	27.5171 mL	68.7928 mL
	5 mM	0.5503 mL	2.7517 mL	5.5034 mL	13.7586 mL
	10 mM	0.2752 mL	1.3759 mL	2.7517 mL	6.8793 mL
	15 mM	0.1834 mL	0.9172 mL	1.8345 mL	4.5862 mL
	20 mM	0.1376 mL	0.6879 mL	1.3759 mL	3.4396 mL
	25 mM	0.1101 mL	0.5503 mL	1.1007 mL	2.7517 mL
	30 mM	0.0917 mL	0.4586 mL	0.9172 mL	2.2931 mL
	40 mM	0.0688 mL	0.3440 mL	0.6879 mL	1.7198 mL
	50 mM	0.0550 mL	0.2752 mL	0.5503 mL	1.3759 mL
	60 mM	0.0459 mL	0.2293 mL	0.4586 mL	1.1465 mL
	80 mM	0.0344 mL	0.1720 mL	0.3440 mL	0.8599 mL
	100 mM	0.0275 mL	0.1376 mL	0.2752 mL	0.6879 mL

WAY-639872 Related Classifications

Others

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WAY-639872796119-18-1WAY639872WAY 639872Drug DerivativeDrug derivativeInhibitorinhibitorinhibit

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WAY-639872

WAY-639872 Related Antibodies

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