α-Ketoglutaric acid disodium dihydrate

Name: α-Ketoglutaric acid disodium dihydrate
Brand: MedChemExpress
SKU: HY-W802699
Rating: 4.5 (0 reviews)

Cat. No.: HY-W802699 Purity: 98.0%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

α-Ketoglutaric acid disodium dihydrate, an important dicarboxylic acid, is an intermediate in the tricarboxylic acid cycle (TCC) and amino acid metabolism. α-Ketoglutaric acid disodium dihydrate can be used as building block chemical for the chemical synthesis of heterocycles, dietary supplement, component of infusion solutions and wound healing compounds, or as main component of new elastomers with a wide range of interesting mechanical and chemical properties.

For research use only. We do not sell to patients.

α-Ketoglutaric acid disodium dihydrate Chemical Structure

CAS No. : 1282616-74-3

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	In-stock	Estimated Time of Arrival: December 31
Solid
10 g	In-stock	Estimated Time of Arrival: December 31
25 g	In-stock	Estimated Time of Arrival: December 31
50 g	In-stock	Estimated Time of Arrival: December 31
100 g	In-stock	Estimated Time of Arrival: December 31
500 g	In-stock	Estimated Time of Arrival: December 31
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Purity & Documentation
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Description

Molecular Weight

226.09

Formula

C₅H₈Na₂O₇

CAS No.

1282616-74-3

Appearance

Solid

Color

White to off-white

SMILES

O=C(CCC(C(O[Na])=O)=O)O[Na].O.O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature, keep dry and cool

In solvent	-80°C	1 year
	-20°C	6 months

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (442.30 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.4230 mL	22.1151 mL	44.2302 mL
5 mM	0.8846 mL	4.4230 mL	8.8460 mL
10 mM	0.4423 mL	2.2115 mL	4.4230 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

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Concentration _(final)

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In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.0%

Select Batch:

Data Sheet (270 KB) SDS (394 KB)

COA (249 KB) HNMR (116 KB)

Handling Instructions (2659 KB)

References

[1]. Otto C, et al. Overproduction and secretion of α-ketoglutaric acid by microorganisms. Appl Microbiol Biotechnol. 2011 Nov;92(4):689-95. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	4.4230 mL	22.1151 mL	44.2302 mL	110.5754 mL
	5 mM	0.8846 mL	4.4230 mL	8.8460 mL	22.1151 mL
	10 mM	0.4423 mL	2.2115 mL	4.4230 mL	11.0575 mL
	15 mM	0.2949 mL	1.4743 mL	2.9487 mL	7.3717 mL
	20 mM	0.2212 mL	1.1058 mL	2.2115 mL	5.5288 mL
	25 mM	0.1769 mL	0.8846 mL	1.7692 mL	4.4230 mL
	30 mM	0.1474 mL	0.7372 mL	1.4743 mL	3.6858 mL
	40 mM	0.1106 mL	0.5529 mL	1.1058 mL	2.7644 mL
	50 mM	0.0885 mL	0.4423 mL	0.8846 mL	2.2115 mL
	60 mM	0.0737 mL	0.3686 mL	0.7372 mL	1.8429 mL
	80 mM	0.0553 mL	0.2764 mL	0.5529 mL	1.3822 mL
	100 mM	0.0442 mL	0.2212 mL	0.4423 mL	1.1058 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.