1-Aminocyclobutanecarboxylic acid

Name: 1-Aminocyclobutanecarboxylic acid
Brand: MedChemExpress
SKU: HY-30006
Rating: 4.5 (0 reviews)

Cat. No.: HY-30006 Purity: 98.0%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

1-Aminocyclobutanecarboxylic acid is a cyclobutane-type amino acid that acts as a substrate analog of enzymes related to plant ethylene synthesis.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

1-Aminocyclobutanecarboxylic acid 화학구조

CAS No. : 22264-50-2

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	해외재고보유	Estimated Time of Arrival: December 31
Solid
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
25 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	해외재고보유	Estimated Time of Arrival: December 31
500 mg	해외재고보유	Estimated Time of Arrival: December 31
1 g	견적 받기
5 g	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

1-Aminocyclobutanecarboxylic acid is a cyclobutane-type amino acid that acts as a substrate analog of enzymes related to plant ethylene synthesis^[1]^[2].

IC₅₀ & Target

NMDA Receptor

Cellular Effect

Cell Line	Type	Value	Description	References
Oocyte	IC₅₀	18.5 μM Compound: 3	Compound was evaluated for in vitro inhibition of oocytes at NMDA receptor. Compound was evaluated for in vitro inhibition of oocytes at NMDA receptor.	[PMID: 7990104]

In Vitro

Derivatives of 1-Aminocyclobutanecarboxylic acid possess potent NMDA receptor antagonistic and anticonvulsant activities^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

115.13

화학식

C₅H₉NO₂

CAS No.

22264-50-2

Appearance

Solid

Color

Off-white to gray

SMILES

O=C(C1(N)CCC1)O

선적

Room temperature in continental US; may vary elsewhere.

보관

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

용액&용해도

In Vitro:

H₂O : 27.78 mg/mL (241.29 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	8.6858 mL	43.4292 mL	86.8583 mL
5 mM	1.7372 mL	8.6858 mL	17.3717 mL
10 mM	0.8686 mL	4.3429 mL	8.6858 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 33.33 mg/mL (289.50 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

순도&문서

Purity: 98.0%

Select Batch:

Data Sheet (273 KB) SDS (394 KB)

COA (250 KB) HNMR (115 KB) MS (187 KB)

Handling Instructions (2659 KB)

References

[1]. Charng YY, et al. The catalytic mechanism of 1-aminocyclopropane-1-carboxylic acid oxidase. Arch Biochem Biophys. 2001;385(1):179-185. [Content Brief]

[2]. Gaoni Y, et al. Synthesis, NMDA receptor antagonist activity, and anticonvulsant action of 1-aminocyclobutanecarboxylic acid derivatives. J Med Chem. 1994;37(25):4288-4296. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	8.6858 mL	43.4292 mL	86.8583 mL	217.1458 mL
	5 mM	1.7372 mL	8.6858 mL	17.3717 mL	43.4292 mL
	10 mM	0.8686 mL	4.3429 mL	8.6858 mL	21.7146 mL
	15 mM	0.5791 mL	2.8953 mL	5.7906 mL	14.4764 mL
	20 mM	0.4343 mL	2.1715 mL	4.3429 mL	10.8573 mL
	25 mM	0.3474 mL	1.7372 mL	3.4743 mL	8.6858 mL
	30 mM	0.2895 mL	1.4476 mL	2.8953 mL	7.2382 mL
	40 mM	0.2171 mL	1.0857 mL	2.1715 mL	5.4286 mL
	50 mM	0.1737 mL	0.8686 mL	1.7372 mL	4.3429 mL
	60 mM	0.1448 mL	0.7238 mL	1.4476 mL	3.6191 mL
	80 mM	0.1086 mL	0.5429 mL	1.0857 mL	2.7143 mL
	100 mM	0.0869 mL	0.4343 mL	0.8686 mL	2.1715 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.