1-Hexanol

製品番号: HY-W032022 純度: 99.35%: Data Sheet SDS COA 取扱説明書
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1-Hexanol, a primary alcohol, is a surfactant that can be employed in industrial processes to enhance interfacial properties. 1-Hexanol uncouples mitochondrial respiration by a non-protonophoric mechanism.

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1-Hexanol 構造式

CAS 番号 : 111-27-3

容量	価格（税別）	在庫状況	数量
Solution
10 mM * 1 mL in Ethanol	USD 33	在庫あり	Estimated Time of Arrival: December 31
Liquid
25 g	$30	在庫あり	Estimated Time of Arrival: December 31
50 g	$50	在庫あり	Estimated Time of Arrival: December 31
100 g	$80	在庫あり	Estimated Time of Arrival: December 31
500 g	$160	在庫あり	Estimated Time of Arrival: December 31
1 kg	$230	在庫あり	Estimated Time of Arrival: December 31

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* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

Other Forms of 1-Hexanol:

1-Hexanol-d₁₃ 在庫あり
1-Hexanol-d₁₁ 在庫あり
1-Hexanol-d₃ お問い合わせ
1-Hexanol-d₅ お問い合わせ
1-Hexanol-d₂ お問い合わせ
1-Hexanol (Standard) お問い合わせ

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純度とドキュメンテーション
参考文献
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製品説明

1-Hexanol, a primary alcohol, is a surfactant that can be employed in industrial processes to enhance interfacial properties^[1]. 1-Hexanol uncouples mitochondrial respiration by a non-protonophoric mechanism^[2].

体外実験

1-Hexanol (0-16 µmol/mg mitochondrial protein) dose-dependently modulates mitochondrial respiration, affects the membrane potential, and exhibits uncoupling effect by affecting the pump function of the mitochondrial respiratory chain^[2].
1-Hexanol (0-20 mM) activates S1 Mg-ATPase, increases the affinity of S1 for actin with the presence of ATP^[3].
.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

体内実験

Animal Model:	Sprague-Dawley rats^[1]
Dosage:	50-100 mg/kg
Administration:	ip, single dose
Result:	Increased the secretion of prolactin and ACTH.

分子量

102.18

分子式

C₆H₁₄O

CAS 番号

111-27-3

Appearance

Liquid (Density: 0.820 g/cm³)

Color

Colorless to light yellow

SMILES

OCCCCCC

Initial Source

Animals

Alfalfa Plant Bug

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Store at room temperature 3 years

*In solvent : -80°C, 6 months; -20°C, 1 month (Store at room temperature 3 years)

溶剤 & 溶解度

体外:

Ethanol : 100 mg/mL (978.67 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	9.7867 mL	48.9333 mL	97.8665 mL
5 mM	1.9573 mL	9.7867 mL	19.5733 mL
10 mM	0.9787 mL	4.8933 mL	9.7867 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

体内:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% EtOH 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (24.47 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% EtOH 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (24.47 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% EtOH 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (24.47 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 99.35%

Select Batch:

データシート (267 KB) SDS (605 KB)

COA (240 KB) HNMR (116 KB) GC (216 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Cuong V Nguyen, et al. Surface potential of 1-hexanol solution: comparison with methyl isobutyl carbinol. J Phys Chem B. 2013 Jun 27;117(25):7615-20. [Content Brief]

[2]. M Canton, et al. The nature of uncoupling by n-hexane, 1-hexanethiol and 1-hexanol in rat liver mitochondria. Biochim Biophys Acta. 1996 May 20;1274(1-2):39-47. [Content Brief]

[3]. Komatsu H, et al., Modulation of actomyosin motor function by 1-hexanol. J Muscle Res Cell Motil. 2004;25(1):77-85 [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

Ethanol	1 mM	9.7867 mL	48.9333 mL	97.8665 mL	244.6663 mL
	5 mM	1.9573 mL	9.7867 mL	19.5733 mL	48.9333 mL
	10 mM	0.9787 mL	4.8933 mL	9.7867 mL	24.4666 mL
	15 mM	0.6524 mL	3.2622 mL	6.5244 mL	16.3111 mL
	20 mM	0.4893 mL	2.4467 mL	4.8933 mL	12.2333 mL
	25 mM	0.3915 mL	1.9573 mL	3.9147 mL	9.7867 mL
	30 mM	0.3262 mL	1.6311 mL	3.2622 mL	8.1555 mL
	40 mM	0.2447 mL	1.2233 mL	2.4467 mL	6.1167 mL
	50 mM	0.1957 mL	0.9787 mL	1.9573 mL	4.8933 mL
	60 mM	0.1631 mL	0.8156 mL	1.6311 mL	4.0778 mL
	80 mM	0.1223 mL	0.6117 mL	1.2233 mL	3.0583 mL
	100 mM	0.0979 mL	0.4893 mL	0.9787 mL	2.4467 mL

1-Hexanol Related Classifications

Others

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量		濃度		体積		分子量 *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）	×	体積 _（開始）	=	濃度 _（終了）	×	体積 _（終了）
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1-Hexanol111-27-3Biochemical Assay ReagentsEnvironmental PollutantsMitochondrial MetabolismEnvironmental ContaminantsInhibitorinhibitorinhibit

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