2-Aminoindan-2-phosphonic acid

Name: 2-Aminoindan-2-phosphonic acid
Brand: MedChemExpress
SKU: HY-W004494
Rating: 4.5 (1 reviews)

製品番号: HY-W004494 純度: 99.55%: Data Sheet SDS COA 取扱説明書
FAQs
Technical Support

2-Aminoindan-2-phosphonic acid is an inhibitor of phenylalanine ammonia-lyase (PAL). 2-Aminoindan-2-phosphonic acid reduces the biosynthesis and accumulation of total phenolic compounds in the suspension cell culture system of Cistanche.

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2-Aminoindan-2-phosphonic acid 構造式

CAS 番号 : 141120-17-4

容量	価格（税別）	在庫状況	数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	USD 60	在庫あり	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	USD 60	在庫あり	Estimated Time of Arrival: December 31
Solid
10 mg	$55	在庫あり	Estimated Time of Arrival: December 31
25 mg	$110	在庫あり	Estimated Time of Arrival: December 31
50 mg	$175	在庫あり	Estimated Time of Arrival: December 31
100 mg		お問い合わせ
200 mg		お問い合わせ

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* アイテムを追加する前、数量をご選択ください

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カスタマーレビュー

Based on 1 publication(s) in Google Scholar

Other Forms of 2-Aminoindan-2-phosphonic acid:

2-Aminoindan-2-phosphonic acid hydrochloride 在庫あり

顧客検証

•Plants. 2026 Mar 9;15(5):844.

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•関連小分子:

•関連タンパク質:

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

IC₅₀ & Target

Phenylalanine aminolyase (PAL)^[1]

体外実験

2-Aminoindan-2-phosphonic acid (0-2.0 μM; 0-28 days) significantly inhibits PAL activity (reducing it to 35.1%-82.7% of that in untreated cells on days 4-28) and decreases the accumulation of total phenolic compounds, Echinacoside (HY-N0020), Verbascoside (HY-N0021), Cistanoside A (HY-N0023), Tubuloside A (HY-N2155) and Salidroside (HY-N0109); except for Salidroside, PAL activity shows a strong correlation with the accumulation of all tested compounds^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

213.17

分子式

C₉H₁₂NO₃P

CAS 番号

141120-17-4

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=P(O)(C1(CC2=C(C1)C=CC=C2)N)O

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

0.1 M NaOH : 10 mg/mL (46.91 mM; ultrasonic and adjust pH to 10 with 0.1 M NaOH)

H₂O : 5.83 mg/mL (27.35 mM; ultrasonic and warming and adjust pH to 1 with 1 M HCL and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.6911 mL	23.4555 mL	46.9109 mL
5 mM	0.9382 mL	4.6911 mL	9.3822 mL
10 mM	0.4691 mL	2.3455 mL	4.6911 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

純度とドキュメンテーション

純度: 99.55%

Select Batch:

データシート (277 KB) SDS (394 KB)

COA (254 KB) HNMR (246 KB) RP-HPLC (226 KB) LCMS (89 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Hu GS, et al. Effects of 2-aminoindan-2-phosphonic acid treatment on the accumulation of salidroside and four phenylethanoid glycosides in suspension cell culture of Cistanche deserticola. Plant Cell Rep. 2011;30(4):665-674. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / 0.1 M NaOH	1 mM	4.6911 mL	23.4555 mL	46.9109 mL	117.2773 mL
	5 mM	0.9382 mL	4.6911 mL	9.3822 mL	23.4555 mL
	10 mM	0.4691 mL	2.3455 mL	4.6911 mL	11.7277 mL
	15 mM	0.3127 mL	1.5637 mL	3.1274 mL	7.8185 mL
	20 mM	0.2346 mL	1.1728 mL	2.3455 mL	5.8639 mL
	25 mM	0.1876 mL	0.9382 mL	1.8764 mL	4.6911 mL
0.1 M NaOH	30 mM	0.1564 mL	0.7818 mL	1.5637 mL	3.9092 mL
0.1 M NaOH	40 mM	0.1173 mL	0.5864 mL	1.1728 mL	2.9319 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.