4,7-Dichloroquinoline

Name: 4,7-Dichloroquinoline
Brand: MedChemExpress
SKU: HY-59243
Rating: 4.5 (1 reviews)

Cat. No.: HY-59243 Purity: 99.95%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

4,7-Dichloroquinoline is a dichloro-substituted quinoline that can be used for the synthesis of other active compounds.

For research use only. We do not sell to patients.

4,7-Dichloroquinoline Chemical Structure

CAS No. : 86-98-6

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
25 g	In-stock	Estimated Time of Arrival: December 31
50 g	In-stock	Estimated Time of Arrival: December 31
100 g	In-stock	Estimated Time of Arrival: December 31
500 g	In-stock	Estimated Time of Arrival: December 31
1 kg	In-stock	Estimated Time of Arrival: December 31

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of 4,7-Dichloroquinoline:

4,7-Dichloroquinoline-¹⁵N Get quote
4,7-Dichloroquinoline (Standard) Get quote

1 Publications Citing Use of MCE 4,7-Dichloroquinoline

•Anal Chem. 2025 Jun 3;97(21):11099-11109. [Abstract]

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Biological Activity
Purity & Documentation
References
Customer Review

Description

4,7-Dichloroquinoline is a dichloro-substituted quinoline that can be used for the synthesis of other active compounds^[1].

In Vitro

4,7-Dichloroquinoline serves as the starting material for the synthesis of 4-quinolinesulfonyl chloride, 7-quinolinesulfonyl chloride, and quinolinesulfonamides^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

198.05

Formula

C₉H₅Cl₂N

CAS No.

86-98-6

Appearance

Solid

Color

White to light brown

SMILES

ClC1=CC=NC2=CC(Cl)=CC=C21

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (252.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.0492 mL	25.2461 mL	50.4923 mL
5 mM	1.0098 mL	5.0492 mL	10.0985 mL
10 mM	0.5049 mL	2.5246 mL	5.0492 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

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In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.95%

Select Batch:

Data Sheet (273 KB) SDS (597 KB)

COA (251 KB) HNMR (110 KB) RP-HPLC (218 KB)

Handling Instructions (2659 KB)

References

[1]. Marciniec K, et al. Synthesis of 4-and 7-quinolinesulfonamides from 4, 7-dichloroquinoline. Heterocycles. 2009 Jan 1;78(1):93.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.0492 mL	25.2461 mL	50.4923 mL	126.2307 mL
	5 mM	1.0098 mL	5.0492 mL	10.0985 mL	25.2461 mL
	10 mM	0.5049 mL	2.5246 mL	5.0492 mL	12.6231 mL
	15 mM	0.3366 mL	1.6831 mL	3.3662 mL	8.4154 mL
	20 mM	0.2525 mL	1.2623 mL	2.5246 mL	6.3115 mL
	25 mM	0.2020 mL	1.0098 mL	2.0197 mL	5.0492 mL
	30 mM	0.1683 mL	0.8415 mL	1.6831 mL	4.2077 mL
	40 mM	0.1262 mL	0.6312 mL	1.2623 mL	3.1558 mL
	50 mM	0.1010 mL	0.5049 mL	1.0098 mL	2.5246 mL
	60 mM	0.0842 mL	0.4208 mL	0.8415 mL	2.1038 mL
	80 mM	0.0631 mL	0.3156 mL	0.6312 mL	1.5779 mL
	100 mM	0.0505 mL	0.2525 mL	0.5049 mL	1.2623 mL