5-FAM-TEGEARGSVILLK(5-TAMRA)K-NH2 TFA

Cat. No.: HY-P10398 Pureza: 91.94%: Ficha de datos
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5-FAM-TEGEARGSVILLK(5-TAMRA)K-NH2 TFA is a substrate for ADAMTS-4/ADAMTS-5, and can be used to detect ADAMTS-4 or ADAMTS-5 activity.

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5-FAM-TEGEARGSVILLK(5-TAMRA)K-NH2 TFA Estructura química

Tamaño	Stock	Cantidad
1 mg	En stock	Estimated Time of Arrival: December 31
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	Obtener un presupuesto
50 mg	Obtener un presupuesto

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Based on 1 Customer Validation

Other Forms of 5-FAM-TEGEARGSVILLK(5-TAMRA)K-NH2 TFA:

5-FAM-TEGEARGSVILLK(5-TAMRA)K-NH2 Obtener un presupuesto

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•Related Proteins:

Actividad biológica
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Referencias
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Descripciòn

5-FAM-TEGEARGSVILLK(5-TAMRA)K-NH2 TFA is a substrate for ADAMTS-4/ADAMTS-5, and can be used to detect ADAMTS-4 or ADAMTS-5 activity^[1].

Peso molecular

2270.49 (free base)

Fòrmula

C₁₁₁H₁₄₈N₂₂O₃₀.xC₂HF₂O₂

Appearance

Solid

Color

Purple to purplish red

Sequence

{5-FAM}-Thr-Glu-Gly-Glu-Ala-Arg-Gly-Ser-Val-Ile-Leu-Leu-Lys-(5-TAMRA)Lys-NH2

Sequence Shortening

{5-FAM}-TEGEARGSVILLK(5-TAMRA)K-NH2 (TFA)

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad

In Vitro:

DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

Pureza y Documentación

Purity: 91.94%

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Ficha de datos (271 KB) SDS (252 KB)

COA (251 KB) RP-HPLC (258 KB) MS (236 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Zhao P, et al. Discovery of Isoindoline Amide Derivatives as Potent and Orally Bioavailable ADAMTS-4/5 Inhibitors for the Treatment of Osteoarthritis. ACS Pharmacol Transl Sci. 2022 Jun 22;5(7):458-467. [Content Brief]