1. NF-κB
    Autophagy
  2. NF-κB
    Autophagy
  3. Berbamine

Berbamine 

Cat. No.: HY-N0714 Purity: 99.79%
Handling Instructions

Berbamine is a natural compound extracted from traditional Chinese medicine Barberry with anti-tumor, immunomodulatory and cardiovascular effects. Berbamine is a calcium channel blocker.

For research use only. We do not sell to patients.

Berbamine Chemical Structure

Berbamine Chemical Structure

CAS No. : 478-61-5

Size Price Stock Quantity
10 mM * 1  mL in DMSO USD 67 In-stock
Estimated Time of Arrival: December 31
5 mg USD 50 In-stock
Estimated Time of Arrival: December 31
10 mg USD 80 In-stock
Estimated Time of Arrival: December 31
20 mg USD 140 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Berbamine is a natural compound extracted from traditional Chinese medicine Barberry with anti-tumor, immunomodulatory and cardiovascular effects. Berbamine is a calcium channel blocker.

IC50 & Target[1]

NF-κB

 

Molecular Weight

608.72

Formula

C₃₇H₄₀N₂O₆

CAS No.

478-61-5

SMILES

COC1=C(OC2=CC([[email protected]]3([H])CC(C=C4)=CC=C4O5)=C(CCN3C)C=C2OC)C([[email protected]@]6([H])CC7=CC=C(O)C5=C7)=C(CCN6C)C=C1OC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (205.35 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6428 mL 8.2140 mL 16.4279 mL
5 mM 0.3286 mL 1.6428 mL 3.2856 mL
10 mM 0.1643 mL 0.8214 mL 1.6428 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 6.25 mg/mL (10.27 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 6.25 mg/mL (10.27 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

BerbamineNF-κBAutophagyNuclear factor-κBNuclear factor-kappaBInhibitorinhibitorinhibit

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Product Name:
Berbamine
Cat. No.:
HY-N0714
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