1. Metabolic Enzyme/Protease
  2. Pyruvate Kinase

DASA-58 

Cat. No.: HY-19330 Purity: 98.01%
Handling Instructions

DASA-58 is a highly specific small molecule PKM2 activator.

For research use only. We do not sell to patients.

DASA-58 Chemical Structure

DASA-58 Chemical Structure

CAS No. : 1203494-49-8

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 158 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
5 mg USD 144 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
10 mg USD 228 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
50 mg USD 756 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
100 mg USD 1320 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Description

DASA-58 is a highly specific small molecule PKM2 activator. DASA-58 inhibits LPS-induced Hif-1a and IL-1b, as well as the expression of a range of other Hif-1a-dependent genes. Target: Hif DASA-58 enhances PKM2 activity by inducing the tetramer formation.

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 2.2049 mL 11.0246 mL 22.0493 mL
5 mM 0.4410 mL 2.2049 mL 4.4099 mL
10 mM 0.2205 mL 1.1025 mL 2.2049 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

453.53

Formula

C₁₉H₂₃N₃O₆S₂

CAS No.

1203494-49-8

SMILES

NC1=CC=CC(S(=O)(N2CCN(S(=O)(C3=CC=C(OCCO4)C4=C3)=O)CCC2)=O)=C1

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 35 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
DASA-58
Cat. No.:
HY-19330
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