1. Metabolic Enzyme/Protease
  2. HIF/HIF Prolyl-Hydroxylase

DASA-58 

Cat. No.: HY-19330 Purity: 98.01%
Data Sheet SDS Handling Instructions

DASA-58 is a highly specific small molecule PKM2 activator. DASA-58 inhibits LPS-induced Hif-1a and IL-1b, as well as the expression of a range of other Hif-1a-dependent genes.

For research use only. We do not sell to patients.
DASA-58 Chemical Structure

DASA-58 Chemical Structure

CAS No. : 1203494-49-8

Size Price Stock Quantity
10 mM * 1 mL in DMSO $132 In-stock
5 mg $120 In-stock
10 mg $190 In-stock
50 mg $630 In-stock
100 mg $1100 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Description

DASA-58 is a highly specific small molecule PKM2 activator. DASA-58 inhibits LPS-induced Hif-1a and IL-1b, as well as the expression of a range of other Hif-1a-dependent genes. Target: Hif DASA-58 enhances PKM2 activity by inducing the tetramer formation.

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 2.2049 mL 11.0246 mL 22.0493 mL
5 mM 0.4410 mL 2.2049 mL 4.4099 mL
10 mM 0.2205 mL 1.1025 mL 2.2049 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

453.53

Formula

C₁₉H₂₃N₃O₆S₂

CAS No.

1203494-49-8

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 35 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
DASA-58
Cat. No.:
HY-19330
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