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Hexaminolevulinate (hydrochloride)  (Synonyms: Hexyl 5-aminolevulinate hydrochloride; P-1206; 5-Aminolevulinic acid hexyl ester hydrochloride)

製品番号: HY-16045 純度: 99.88%
COA 取扱説明書 Technical Support

Hexaminolevulinate (Hexyl 5-aminolevulinate) hydrochloride, a porphyrin precursor, is a photosensitiser that can be used in photodynamic therapy (PDT) for certain tumor. Hexaminolevulinate hydrochloride can improve the visualisation of bladder tumours.

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Hexaminolevulinate hydrochloride

Hexaminolevulinate (hydrochloride) 構造式

CAS 番号 : 140898-91-5

容量 価格(税別) 在庫状況 数量
>無料サンプル (0.1 - 0.2 mg)   今すぐ申し込む  
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
USD 27 在庫あり
Solution
10 mM * 1 mL in DMSO USD 27 在庫あり
Solid
100 mg $25 在庫あり
500 mg $55 在庫あり
1 g $91 在庫あり
5 g   お問い合わせ  
10 g   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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製品説明

Hexaminolevulinate (Hexyl 5-aminolevulinate) hydrochloride, a porphyrin precursor, is a photosensitiser that can be used in photodynamic therapy (PDT) for certain tumor. Hexaminolevulinate hydrochloride can improve the visualisation of bladder tumours[1][2].

体外実験

Hexaminolevulinate (2.5-100 μM; 4 h in serum-free medium) hydrochloride induces PpIX production in L1210 cell line and pure BM[2].
Hexaminolevulinate (1-100 μM; 4 h in serum-free medium) hydrochloride induces PpIX production in the mixtures of BM with L1210 tumor cells[2].
Hexaminolevulinate (20-100 μM) in combination with increasing doses of blue light illumination from 0 to 120 s results in progressive killing of L1210 cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

臨床実験
分子量

251.75

分子式

C11H22ClNO3

CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

O=C(OCCCCCC)CCC(CN)=O.[H]Cl

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶剤 & 溶解度
体外: 

DMSO : ≥ 100 mg/mL (397.22 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 100 mg/mL (397.22 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9722 mL 19.8610 mL 39.7219 mL
5 mM 0.7944 mL 3.9722 mL 7.9444 mL
10 mM 0.3972 mL 1.9861 mL 3.9722 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始)

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体積 (開始)

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 3.9722 mL 19.8610 mL 39.7219 mL 99.3049 mL
5 mM 0.7944 mL 3.9722 mL 7.9444 mL 19.8610 mL
10 mM 0.3972 mL 1.9861 mL 3.9722 mL 9.9305 mL
15 mM 0.2648 mL 1.3241 mL 2.6481 mL 6.6203 mL
20 mM 0.1986 mL 0.9930 mL 1.9861 mL 4.9652 mL
25 mM 0.1589 mL 0.7944 mL 1.5889 mL 3.9722 mL
30 mM 0.1324 mL 0.6620 mL 1.3241 mL 3.3102 mL
40 mM 0.0993 mL 0.4965 mL 0.9930 mL 2.4826 mL
50 mM 0.0794 mL 0.3972 mL 0.7944 mL 1.9861 mL
60 mM 0.0662 mL 0.3310 mL 0.6620 mL 1.6551 mL
80 mM 0.0497 mL 0.2483 mL 0.4965 mL 1.2413 mL
100 mM 0.0397 mL 0.1986 mL 0.3972 mL 0.9930 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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製品名:
Hexaminolevulinate hydrochloride
製品番号:
HY-16045
数量:
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